000 02122 a2200589 4500
005 20250516110908.0
264 0 _c20130201
008 201302s 0 0 eng d
022 _a1558-8238
024 7 _a10.1172/JCI60777
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aPetrasek, Jan
245 0 0 _aIL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice.
_h[electronic resource]
260 _bThe Journal of clinical investigation
_cOct 2012
300 _a3476-89 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Review
650 0 4 _aAnimals
650 0 4 _aCarrier Proteins
_xbiosynthesis
650 0 4 _aCaspase 1
_xphysiology
650 0 4 _aChemokine CCL2
_xbiosynthesis
650 0 4 _aDrug Evaluation, Preclinical
650 0 4 _aEthanol
_xtoxicity
650 0 4 _aFatty Liver, Alcoholic
_xdrug therapy
650 0 4 _aFemale
650 0 4 _aHepatocytes
_xmetabolism
650 0 4 _aInflammasomes
_xphysiology
650 0 4 _aInterleukin 1 Receptor Antagonist Protein
_xtherapeutic use
650 0 4 _aInterleukin-1alpha
_xbiosynthesis
650 0 4 _aInterleukin-1beta
_xbiosynthesis
650 0 4 _aKupffer Cells
_xpathology
650 0 4 _aLiver Cirrhosis
_xetiology
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMice, Knockout
650 0 4 _aNLR Family, Pyrin Domain-Containing 3 Protein
650 0 4 _aReceptors, Interleukin-1 Type I
_xdeficiency
650 0 4 _aRecombinant Proteins
_xtherapeutic use
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aToll-Like Receptor 4
_xphysiology
650 0 4 _aUp-Regulation
_xdrug effects
700 1 _aBala, Shashi
700 1 _aCsak, Timea
700 1 _aLippai, Dora
700 1 _aKodys, Karen
700 1 _aMenashy, Victoria
700 1 _aBarrieau, Matthew
700 1 _aMin, So-Yun
700 1 _aKurt-Jones, Evelyn A
700 1 _aSzabo, Gyongyi
773 0 _tThe Journal of clinical investigation
_gvol. 122
_gno. 10
_gp. 3476-89
856 4 0 _uhttps://doi.org/10.1172/JCI60777
_zAvailable from publisher's website
999 _c22074265
_d22074265