| 000 | 01374 a2200337 4500 | ||
|---|---|---|---|
| 005 | 20250516104822.0 | ||
| 264 | 0 | _c20121231 | |
| 008 | 201212s 0 0 eng d | ||
| 022 | _a1520-4804 | ||
| 024 | 7 |
_a10.1021/jm300493m _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aHochdörffer, Katrin | |
| 245 | 0 | 0 |
_aDevelopment of novel bisphosphonate prodrugs of doxorubicin for targeting bone metastases that are cleaved pH dependently or by cathepsin B: synthesis, cleavage properties, and binding properties to hydroxyapatite as well as bone matrix. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cSep 2012 |
||
| 300 |
_a7502-15 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 |
_aBone Neoplasms _xdrug therapy |
| 650 | 0 | 4 |
_aBone and Bones _xmetabolism |
| 650 | 0 | 4 |
_aCathepsin B _xmetabolism |
| 650 | 0 | 4 |
_aDiphosphonates _xmetabolism |
| 650 | 0 | 4 |
_aDoxorubicin _xmetabolism |
| 650 | 0 | 4 |
_aDurapatite _xmetabolism |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aHydrogen-Ion Concentration |
| 650 | 0 | 4 |
_aProdrugs _xmetabolism |
| 700 | 1 | _aAbu Ajaj, Khalid | |
| 700 | 1 | _aSchäfer-Obodozie, Cynthia | |
| 700 | 1 | _aKratz, Felix | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 55 _gno. 17 _gp. 7502-15 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm300493m _zAvailable from publisher's website |
| 999 |
_c22014990 _d22014990 |
||