000 01888 a2200553 4500
005 20250516104508.0
264 0 _c20130219
008 201302s 0 0 eng d
022 _a1932-6203
024 7 _a10.1371/journal.pone.0042863
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHaaß, Wiltrud
245 0 0 _aThe proteolytic activity of separase in BCR-ABL-positive cells is increased by imatinib.
_h[electronic resource]
260 _bPloS one
_c2012
300 _ae42863 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aBenzamides
650 0 4 _aBlast Crisis
_xdrug therapy
650 0 4 _aCell Cycle Proteins
_xgenetics
650 0 4 _aCyclin B1
_xgenetics
650 0 4 _aDrug Resistance, Neoplasm
_xdrug effects
650 0 4 _aEndopeptidases
_xgenetics
650 0 4 _aFusion Proteins, bcr-abl
_xgenetics
650 0 4 _aGenomic Instability
_xdrug effects
650 0 4 _aHL-60 Cells
650 0 4 _aHumans
650 0 4 _aImatinib Mesylate
650 0 4 _aK562 Cells
650 0 4 _aLeukemia, Myelogenous, Chronic, BCR-ABL Positive
_xdrug therapy
650 0 4 _aNeoplasm Proteins
_xgenetics
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aPiperazines
_xpharmacology
650 0 4 _aProtein Phosphatase 2
_xgenetics
650 0 4 _aProteolysis
650 0 4 _aPyrimidines
_xpharmacology
650 0 4 _aSecurin
650 0 4 _aSeparase
650 0 4 _aU937 Cells
700 1 _aStehle, Michael
700 1 _aNittka, Stefanie
700 1 _aGiehl, Michelle
700 1 _aSchrotz-King, Petra
700 1 _aFabarius, Alice
700 1 _aHofmann, Wolf-Karsten
700 1 _aSeifarth, Wolfgang
773 0 _tPloS one
_gvol. 7
_gno. 8
_gp. e42863
856 4 0 _uhttps://doi.org/10.1371/journal.pone.0042863
_zAvailable from publisher's website
999 _c22005429
_d22005429