000 | 01701 a2200481 4500 | ||
---|---|---|---|
005 | 20250516103559.0 | ||
264 | 0 | _c20130317 | |
008 | 201303s 0 0 eng d | ||
022 | _a2045-2322 | ||
024 | 7 |
_a10.1038/srep00535 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aTohda, Chihiro | |
245 | 0 | 0 |
_aDiosgenin is an exogenous activator of 1,25D₃-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD mice. _h[electronic resource] |
260 |
_bScientific reports _c2012 |
||
300 |
_a535 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 |
_aAlzheimer Disease _xdrug therapy |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aAntibodies, Monoclonal _ximmunology |
650 | 0 | 4 |
_aAntibodies, Neutralizing _ximmunology |
650 | 0 | 4 |
_aAxons _xdrug effects |
650 | 0 | 4 |
_aCerebellar Cortex _xdrug effects |
650 | 0 | 4 |
_aDiosgenin _xadministration & dosage |
650 | 0 | 4 | _aDisease Models, Animal |
650 | 0 | 4 | _aFemale |
650 | 0 | 4 | _aGene Knockdown Techniques |
650 | 0 | 4 | _aMale |
650 | 0 | 4 |
_aMemory Disorders _xdrug therapy |
650 | 0 | 4 | _aMice |
650 | 0 | 4 | _aMolecular Docking Simulation |
650 | 0 | 4 |
_aNeurons _xdrug effects |
650 | 0 | 4 | _aPlaque, Amyloid |
650 | 0 | 4 |
_aPresynaptic Terminals _xdrug effects |
650 | 0 | 4 | _aProtein Conformation |
650 | 0 | 4 |
_aProtein Disulfide-Isomerases _xchemistry |
650 | 0 | 4 |
_aProtein Kinase Inhibitors _xpharmacology |
700 | 1 | _aUrano, Takuya | |
700 | 1 | _aUmezaki, Masahito | |
700 | 1 | _aNemere, Ilka | |
700 | 1 | _aKuboyama, Tomoharu | |
773 | 0 |
_tScientific reports _gvol. 2 _gp. 535 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1038/srep00535 _zAvailable from publisher's website |
999 |
_c21979558 _d21979558 |