000			02045 a2200589 4500
005			20250516103037.0
264		0	_c20130122
008			201301s 0 0 eng d
022			_a1878-4186
024	7		_a10.1016/j.str.2012.06.013 _2doi
040			_aNLM _beng _cNLM
100	1		_aMazhab-Jafari, Mohammad T
245	0	0	_aAn autoinhibited noncanonical mechanism of GTP hydrolysis by Rheb maintains mTORC1 homeostasis. _h[electronic resource]
260			_bStructure (London, England : 1993) _cSep 2012
300			_a1528-39 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
650	0	4	_aAmino Acid Motifs
650	0	4	_aAmino Acid Substitution
650	0	4	_aAnimals
650	0	4	_aCatalytic Domain
650	0	4	_aCrystallography, X-Ray
650	0	4	_aEnzyme Activation
650	0	4	_aGuanosine Triphosphate _xchemistry
650	0	4	_aHEK293 Cells
650	0	4	_aHeLa Cells
650	0	4	_aHomeostasis
650	0	4	_aHumans
650	0	4	_aHydrogen Bonding
650	0	4	_aHydrolysis
650	0	4	_aKinetics
650	0	4	_aMechanistic Target of Rapamycin Complex 1
650	0	4	_aMice
650	0	4	_aModels, Molecular
650	0	4	_aMonomeric GTP-Binding Proteins _xchemistry
650	0	4	_aMultiprotein Complexes
650	0	4	_aMutagenesis, Site-Directed
650	0	4	_aNeuropeptides _xchemistry
650	0	4	_aProtein Binding
650	0	4	_aProteins _xmetabolism
650	0	4	_aRas Homolog Enriched in Brain Protein
650	0	4	_aRibosomal Protein S6 Kinases, 70-kDa _xmetabolism
650	0	4	_aTOR Serine-Threonine Kinases
650	0	4	_aThermodynamics
700	1		_aMarshall, Christopher B
700	1		_aIshiyama, Noboru
700	1		_aHo, Jason
700	1		_aDi Palma, Vanessa
700	1		_aStambolic, Vuk
700	1		_aIkura, Mitsuhiko
773	0		_tStructure (London, England : 1993) _gvol. 20 _gno. 9 _gp. 1528-39
856	4	0	_uhttps://doi.org/10.1016/j.str.2012.06.013 _zAvailable from publisher's website
999			_c21963496 _d21963496