000 01560 a2200433 4500
005 20250516102744.0
264 0 _c20130423
008 201304s 0 0 eng d
022 _a1875-8908
024 7 _a10.3233/JAD-2012-121129
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBialopiotrowicz, Emilia
245 0 0 _aHighly pathogenic Alzheimer's disease presenilin 1 P117R mutation causes a specific increase in p53 and p21 protein levels and cell cycle dysregulation in human lymphocytes.
_h[electronic resource]
260 _bJournal of Alzheimer's disease : JAD
_c2012
300 _a397-415 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aAlzheimer Disease
_xgenetics
650 0 4 _aApoptosis
_xgenetics
650 0 4 _aB-Lymphocytes
_xmetabolism
650 0 4 _aCell Cycle
_xgenetics
650 0 4 _aCyclin-Dependent Kinase Inhibitor p21
_xgenetics
650 0 4 _aFemale
650 0 4 _aHEK293 Cells
650 0 4 _aHumans
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aMutation
650 0 4 _aPresenilin-1
_xgenetics
650 0 4 _aTumor Suppressor Protein p53
_xgenetics
700 1 _aSzybinska, Aleksandra
700 1 _aKuzniewska, Bozena
700 1 _aBuizza, Laura
700 1 _aUberti, Daniela
700 1 _aKuznicki, Jacek
700 1 _aWojda, Urszula
773 0 _tJournal of Alzheimer's disease : JAD
_gvol. 32
_gno. 2
_gp. 397-415
856 4 0 _uhttps://doi.org/10.3233/JAD-2012-121129
_zAvailable from publisher's website
999 _c21956592
_d21956592