| 000 | 02564 a2200733 4500 | ||
|---|---|---|---|
| 005 | 20250516102555.0 | ||
| 264 | 0 | _c20121126 | |
| 008 | 201211s 0 0 eng d | ||
| 022 | _a1520-4804 | ||
| 024 | 7 |
_a10.1021/jm300601d _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aHuber, John D | |
| 245 | 0 | 0 |
_aIdentification of a potent sodium hydrogen exchanger isoform 1 (NHE1) inhibitor with a suitable profile for chronic dosing and demonstrated cardioprotective effects in a preclinical model of myocardial infarction in the rat. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cAug 2012 |
||
| 300 |
_a7114-40 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aBenzamides _xchemical synthesis |
| 650 | 0 | 4 | _aBiological Availability |
| 650 | 0 | 4 |
_aBlood Platelets _xcytology |
| 650 | 0 | 4 | _aCell Line |
| 650 | 0 | 4 | _aCell Membrane Permeability |
| 650 | 0 | 4 | _aCell Size |
| 650 | 0 | 4 | _aCytochrome P-450 Enzyme Inhibitors |
| 650 | 0 | 4 | _aDogs |
| 650 | 0 | 4 | _aERG1 Potassium Channel |
| 650 | 0 | 4 |
_aEther-A-Go-Go Potassium Channels _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aGuanidines _xchemical synthesis |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 | _aMembranes, Artificial |
| 650 | 0 | 4 |
_aMicrosomes, Liver _xmetabolism |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 |
_aMyocardial Infarction _xdrug therapy |
| 650 | 0 | 4 |
_aMyocardial Reperfusion Injury _xprevention & control |
| 650 | 0 | 4 | _aPermeability |
| 650 | 0 | 4 |
_aProtein Isoforms _xantagonists & inhibitors |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 | _aRats, Sprague-Dawley |
| 650 | 0 | 4 | _aSodium-Hydrogen Exchanger 1 |
| 650 | 0 | 4 |
_aSodium-Hydrogen Exchangers _xantagonists & inhibitors |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 700 | 1 | _aBentzien, Jörg | |
| 700 | 1 | _aBoyer, Stephen J | |
| 700 | 1 | _aBurke, Jennifer | |
| 700 | 1 | _aDe Lombaert, Stéphane | |
| 700 | 1 | _aEickmeier, Christian | |
| 700 | 1 | _aGuo, Xin | |
| 700 | 1 | _aHaist, James V | |
| 700 | 1 | _aHickey, Eugene R | |
| 700 | 1 | _aKaplita, Paul | |
| 700 | 1 | _aKarmazyn, Morris | |
| 700 | 1 | _aKemper, Raymond | |
| 700 | 1 | _aKennedy, Charles A | |
| 700 | 1 | _aKirrane, Thomas | |
| 700 | 1 | _aMadwed, Jeffrey B | |
| 700 | 1 | _aMainolfi, Elizabeth | |
| 700 | 1 | _aNagaraja, Nelamangara | |
| 700 | 1 | _aSoleymanzadeh, Fariba | |
| 700 | 1 | _aSwinamer, Alan | |
| 700 | 1 | _aEldrup, Anne B | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 55 _gno. 16 _gp. 7114-40 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm300601d _zAvailable from publisher's website |
| 999 |
_c21951205 _d21951205 |
||