000 02672 a2200745 4500
005 20250516102351.0
264 0 _c20121029
008 201210s 0 0 eng d
022 _a1524-4636
024 7 _a10.1161/ATVBAHA.112.253906
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aCollin, Nicolas
245 0 0 _aLufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo.
_h[electronic resource]
260 _bArteriosclerosis, thrombosis, and vascular biology
_cSep 2012
300 _a2185-98 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
650 0 4 _aAmino Acid Sequence
650 0 4 _aAnimals
650 0 4 _aAnti-Inflammatory Agents
_xchemistry
650 0 4 _aBlood Coagulation
_xdrug effects
650 0 4 _aCalorimetry
650 0 4 _aCell Line, Tumor
650 0 4 _aChlorides
650 0 4 _aCloning, Molecular
650 0 4 _aDisease Models, Animal
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aFactor Xa
_xmetabolism
650 0 4 _aFactor Xa Inhibitors
650 0 4 _aFemale
650 0 4 _aFerric Compounds
650 0 4 _aFibrinolytic Agents
_xchemistry
650 0 4 _aHEK293 Cells
650 0 4 _aHumans
650 0 4 _aInflammation
_xblood
650 0 4 _aInsect Proteins
_xchemistry
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMolecular Sequence Data
650 0 4 _aMolecular Weight
650 0 4 _aPartial Thromboplastin Time
650 0 4 _aProtein Binding
650 0 4 _aProthrombin Time
650 0 4 _aPsychodidae
_xchemistry
650 0 4 _aRats
650 0 4 _aReceptor, PAR-2
_xantagonists & inhibitors
650 0 4 _aRecombinant Proteins
_xantagonists & inhibitors
650 0 4 _aSalivary Glands
_xchemistry
650 0 4 _aSurface Plasmon Resonance
650 0 4 _aThromboplastin
_xantagonists & inhibitors
650 0 4 _aThrombosis
_xblood
650 0 4 _aTime Factors
700 1 _aAssumpção, Teresa C F
700 1 _aMizurini, Daniella M
700 1 _aGilmore, Dana C
700 1 _aDutra-Oliveira, Angélica
700 1 _aKotsyfakis, Michalis
700 1 _aSá-Nunes, Anderson
700 1 _aTeixeira, Clarissa
700 1 _aRibeiro, José M C
700 1 _aMonteiro, Robson Q
700 1 _aValenzuela, Jesus G
700 1 _aFrancischetti, Ivo M B
773 0 _tArteriosclerosis, thrombosis, and vascular biology
_gvol. 32
_gno. 9
_gp. 2185-98
856 4 0 _uhttps://doi.org/10.1161/ATVBAHA.112.253906
_zAvailable from publisher's website
999 _c21944935
_d21944935