000 01340 a2200361 4500
005 20250516101024.0
264 0 _c20121126
008 201211s 0 0 eng d
022 _a1520-4995
024 7 _a10.1021/bi300377d
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWennerstrand, Patricia
245 0 0 _aStructural characteristics determine the cause of the low enzyme activity of two thiopurine S-methyltransferase allelic variants: a biophysical characterization of TPMT*2 and TPMT*5.
_h[electronic resource]
260 _bBiochemistry
_cJul 2012
300 _a5912-20 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAlleles
650 0 4 _aAmino Acid Sequence
650 0 4 _aCatalytic Domain
_xgenetics
650 0 4 _aEnzyme Activation
_xgenetics
650 0 4 _aGenetic Variation
_xgenetics
650 0 4 _aHumans
650 0 4 _aMethyltransferases
_xchemistry
650 0 4 _aMolecular Sequence Data
700 1 _aDametto, Paolo
700 1 _aHennig, Janosch
700 1 _aKlingstedt, Therése
700 1 _aSkoglund, Karin
700 1 _aAppell, Malin Lindqvist
700 1 _aMårtensson, Lars-Göran
773 0 _tBiochemistry
_gvol. 51
_gno. 30
_gp. 5912-20
856 4 0 _uhttps://doi.org/10.1021/bi300377d
_zAvailable from publisher's website
999 _c21907081
_d21907081