000 01880 a2200505 4500
005 20250516100910.0
264 0 _c20130124
008 201301s 0 0 eng d
022 _a1879-3177
024 7 _a10.1016/j.tiv.2012.06.008
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHayashi, Kazuhiko
245 0 0 _aTwo-stage bottom-up tiered approach combining several alternatives for identification of eye irritation potential of chemicals including insoluble or volatile substances.
_h[electronic resource]
260 _bToxicology in vitro : an international journal published in association with BIBRA
_cOct 2012
300 _a1199-208 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnimal Testing Alternatives
650 0 4 _aAnimals
650 0 4 _aCattle
650 0 4 _aCell Line
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aChorioallantoic Membrane
_xdrug effects
650 0 4 _aCornea
_xdrug effects
650 0 4 _aCorneal Opacity
_xchemically induced
650 0 4 _aEye
_xdrug effects
650 0 4 _aIrritants
_xclassification
650 0 4 _aPredictive Value of Tests
650 0 4 _aReproducibility of Results
650 0 4 _aResearch Design
650 0 4 _aSolubility
650 0 4 _aToxicity Tests, Acute
_xmethods
650 0 4 _aVolatile Organic Compounds
_xtoxicity
650 0 4 _aVolatilization
700 1 _aMori, Taeko
700 1 _aAbo, Takayuki
700 1 _aOoshima, Kenichi
700 1 _aHayashi, Takumi
700 1 _aKomano, Tomoko
700 1 _aTakahashi, Yutaka
700 1 _aSakaguchi, Hitoshi
700 1 _aTakatsu, Akihiko
700 1 _aNishiyama, Naohiro
773 0 _tToxicology in vitro : an international journal published in association with BIBRA
_gvol. 26
_gno. 7
_gp. 1199-208
856 4 0 _uhttps://doi.org/10.1016/j.tiv.2012.06.008
_zAvailable from publisher's website
999 _c21903772
_d21903772