000 02015 a2200565 4500
005 20250516095718.0
264 0 _c20120913
008 201209s 0 0 eng d
022 _a1097-4180
024 7 _a10.1016/j.immuni.2012.03.022
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aJiang, Xiaomo
245 0 0 _aUbiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response.
_h[electronic resource]
260 _bImmunity
_cJun 2012
300 _a959-73 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aCell-Free System
650 0 4 _aDEAD Box Protein 58
650 0 4 _aDEAD-box RNA Helicases
_xchemistry
650 0 4 _aEncephalomyocarditis virus
_xgenetics
650 0 4 _aFibroblasts
_xmetabolism
650 0 4 _aHEK293 Cells
_xmetabolism
650 0 4 _aHumans
650 0 4 _aInterferon Regulatory Factor-3
_xmetabolism
650 0 4 _aInterferon-Induced Helicase, IFIH1
650 0 4 _aInterferon-beta
_xbiosynthesis
650 0 4 _aMice
650 0 4 _aMultiprotein Complexes
650 0 4 _aMutagenesis, Site-Directed
650 0 4 _aPolyubiquitin
_xmetabolism
650 0 4 _aProtein Binding
650 0 4 _aProtein Interaction Mapping
650 0 4 _aProtein Processing, Post-Translational
650 0 4 _aProtein Structure, Tertiary
650 0 4 _aRNA, Viral
_xmetabolism
650 0 4 _aReceptors, Immunologic
650 0 4 _aRecombinant Fusion Proteins
_xchemistry
650 0 4 _aSignal Transduction
_xphysiology
650 0 4 _aStructure-Activity Relationship
650 0 4 _aUbiquitination
700 1 _aKinch, Lisa N
700 1 _aBrautigam, Chad A
700 1 _aChen, Xiang
700 1 _aDu, Fenghe
700 1 _aGrishin, Nick V
700 1 _aChen, Zhijian J
773 0 _tImmunity
_gvol. 36
_gno. 6
_gp. 959-73
856 4 0 _uhttps://doi.org/10.1016/j.immuni.2012.03.022
_zAvailable from publisher's website
999 _c21870374
_d21870374