000			02212 a2200589 4500
005			20250516094414.0
264		0	_c20130117
008			201301s 0 0 eng d
022			_a1521-009X
024	7		_a10.1124/dmd.112.046193 _2doi
040			_aNLM _beng _cNLM
100	1		_aMénochet, Karelle
245	0	0	_aUse of mechanistic modeling to assess interindividual variability and interspecies differences in active uptake in human and rat hepatocytes. _h[electronic resource]
260			_bDrug metabolism and disposition: the biological fate of chemicals _cSep 2012
300			_a1744-56 p. _bdigital
500			_aPublication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAngiotensin II Type 1 Receptor Blockers _xmetabolism
650	0	4	_aAnimals
650	0	4	_aAntihypertensive Agents _xmetabolism
650	0	4	_aBenzimidazoles _xmetabolism
650	0	4	_aBenzoates _xmetabolism
650	0	4	_aBiological Transport
650	0	4	_aBosentan
650	0	4	_aCarbamates _xmetabolism
650	0	4	_aDose-Response Relationship, Drug
650	0	4	_aDrug Interactions
650	0	4	_aFluorobenzenes _xmetabolism
650	0	4	_aHepatocytes _xdrug effects
650	0	4	_aHumans
650	0	4	_aHydroxymethylglutaryl-CoA Reductase Inhibitors _xmetabolism
650	0	4	_aHypoglycemic Agents _xmetabolism
650	0	4	_aKinetics
650	0	4	_aModels, Biological
650	0	4	_aOrganic Anion Transporters _xdrug effects
650	0	4	_aPiperidines _xmetabolism
650	0	4	_aPravastatin _xmetabolism
650	0	4	_aPyrimidines _xmetabolism
650	0	4	_aQuinolines _xmetabolism
650	0	4	_aRats
650	0	4	_aRosuvastatin Calcium
650	0	4	_aSpecies Specificity
650	0	4	_aSulfonamides _xmetabolism
650	0	4	_aTelmisartan
650	0	4	_aTetrazoles _xmetabolism
650	0	4	_aValine _xanalogs & derivatives
650	0	4	_aValsartan
700	1		_aKenworthy, Kathryn E
700	1		_aHouston, J Brian
700	1		_aGaletin, Aleksandra
773	0		_tDrug metabolism and disposition: the biological fate of chemicals _gvol. 40 _gno. 9 _gp. 1744-56
856	4	0	_uhttps://doi.org/10.1124/dmd.112.046193 _zAvailable from publisher's website
999			_c21836067 _d21836067