000 02506 a2200637 4500
005 20250516093352.0
264 0 _c20120917
008 201209s 0 0 eng d
022 _a1937-9145
024 7 _a10.1126/scisignal.2002767
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aInoue, Makoto
245 0 0 _aInterferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome.
_h[electronic resource]
260 _bScience signaling
_cMay 2012
300 _ara38 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aApoptosis Regulatory Proteins
650 0 4 _aCARD Signaling Adaptor Proteins
650 0 4 _aCD4-Positive T-Lymphocytes
_xtransplantation
650 0 4 _aCarrier Proteins
_xgenetics
650 0 4 _aCaspase 1
_xphysiology
650 0 4 _aCytoskeletal Proteins
_xdeficiency
650 0 4 _aDisease Models, Animal
650 0 4 _aEncephalomyelitis, Autoimmune, Experimental
_xdrug therapy
650 0 4 _aEnzyme Activation
650 0 4 _aGene Expression Regulation
_xdrug effects
650 0 4 _aInflammasomes
_xphysiology
650 0 4 _aInterferon beta-1b
650 0 4 _aInterferon-beta
_xtherapeutic use
650 0 4 _aInterleukin-1beta
_xbiosynthesis
650 0 4 _aMacrophages
_xphysiology
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMice, Knockout
650 0 4 _aMice, Transgenic
650 0 4 _aNLR Family, Pyrin Domain-Containing 3 Protein
650 0 4 _aNeuropeptides
_xantagonists & inhibitors
650 0 4 _aProto-Oncogene Proteins c-vav
_xantagonists & inhibitors
650 0 4 _aReactive Oxygen Species
_xmetabolism
650 0 4 _aReceptor, Interferon alpha-beta
_xdeficiency
650 0 4 _aRecombinant Proteins
_xtherapeutic use
650 0 4 _aSuppressor of Cytokine Signaling 1 Protein
650 0 4 _aSuppressor of Cytokine Signaling Proteins
_xantagonists & inhibitors
650 0 4 _arac GTP-Binding Proteins
_xantagonists & inhibitors
650 0 4 _arac1 GTP-Binding Protein
700 1 _aWilliams, Kristi L
700 1 _aOliver, Timothy
700 1 _aVandenabeele, Peter
700 1 _aRajan, Jayant V
700 1 _aMiao, Edward A
700 1 _aShinohara, Mari L
773 0 _tScience signaling
_gvol. 5
_gno. 225
_gp. ra38
856 4 0 _uhttps://doi.org/10.1126/scisignal.2002767
_zAvailable from publisher's website
999 _c21806914
_d21806914