000 01562 a2200421 4500
005 20250511225118.0
264 0 _c19910110
008 199101s 0 0 eng d
022 _a0027-8424
024 7 _a10.1073/pnas.87.22.8697
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKoshy, T I
245 0 0 _aChanging the invariant proline-30 of rat and Drosophila melanogaster cytochromes c to alanine or valine destabilizes the heme crevice more than the overall conformation.
_h[electronic resource]
260 _bProceedings of the National Academy of Sciences of the United States of America
_cNov 1990
300 _a8697-701 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAlanine
650 0 4 _aAnimals
650 0 4 _aBinding Sites
650 0 4 _aCloning, Molecular
650 0 4 _aCytochrome c Group
_xchemistry
650 0 4 _aDrosophila melanogaster
650 0 4 _aHeme
650 0 4 _aHot Temperature
650 0 4 _aProline
650 0 4 _aProtein Conformation
_xdrug effects
650 0 4 _aRats
650 0 4 _aRecombinant Proteins
650 0 4 _aSpectrum Analysis
650 0 4 _aStructure-Activity Relationship
650 0 4 _aUrea
_xpharmacology
650 0 4 _aValine
700 1 _aLuntz, T L
700 1 _aSchejter, A
700 1 _aMargoliash, E
773 0 _tProceedings of the National Academy of Sciences of the United States of America
_gvol. 87
_gno. 22
_gp. 8697-701
856 4 0 _uhttps://doi.org/10.1073/pnas.87.22.8697
_zAvailable from publisher's website
999 _c2180290
_d2180290