000 01736 a2200505 4500
005 20250516093212.0
264 0 _c20130805
008 201308s 0 0 eng d
022 _a1365-2125
024 7 _a10.1111/j.1365-2125.2012.04339.x
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aTong, Gary
245 0 0 _aA contrast in safety, pharmacokinetics and pharmacodynamics across age groups after a single 50 mg oral dose of the γ-secretase inhibitor avagacestat.
_h[electronic resource]
260 _bBritish journal of clinical pharmacology
_cJan 2013
300 _a136-45 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdministration, Oral
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aAlzheimer Disease
_xdrug therapy
650 0 4 _aAmyloid Precursor Protein Secretases
_xantagonists & inhibitors
650 0 4 _aDouble-Blind Method
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aOxadiazoles
_xadverse effects
650 0 4 _aSulfonamides
_xadverse effects
700 1 _aWang, Jun-Sheng
700 1 _aSverdlov, Oleksandr
700 1 _aHuang, Shu-Pang
700 1 _aSlemmon, Randy
700 1 _aCroop, Robert
700 1 _aCastaneda, Lorna
700 1 _aGu, Huidong
700 1 _aWong, Oi
700 1 _aLi, Hewei
700 1 _aBerman, Robert M
700 1 _aSmith, Christina
700 1 _aAlbright, Charles F
700 1 _aDockens, Randy
773 0 _tBritish journal of clinical pharmacology
_gvol. 75
_gno. 1
_gp. 136-45
856 4 0 _uhttps://doi.org/10.1111/j.1365-2125.2012.04339.x
_zAvailable from publisher's website
999 _c21801859
_d21801859