000 02064 a2200601 4500
005 20250516090906.0
264 0 _c20121113
008 201211s 0 0 eng d
022 _a1476-5551
024 7 _a10.1038/leu.2012.116
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBlackburn, J S
245 0 0 _aNotch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency.
_h[electronic resource]
260 _bLeukemia
_cSep 2012
300 _a2069-78 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAnimals, Genetically Modified
650 0 4 _aApoptosis
650 0 4 _aBiomarkers, Tumor
_xgenetics
650 0 4 _aBlotting, Western
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
650 0 4 _aCell Transformation, Neoplastic
650 0 4 _aGene Expression Profiling
650 0 4 _aGene Expression Regulation, Leukemic
650 0 4 _aHumans
650 0 4 _aMice
650 0 4 _aOligonucleotide Array Sequence Analysis
650 0 4 _aPrecursor T-Cell Lymphoblastic Leukemia-Lymphoma
_xmetabolism
650 0 4 _aProto-Oncogene Proteins c-myc
_xmetabolism
650 0 4 _aRNA, Messenger
_xgenetics
650 0 4 _aReal-Time Polymerase Chain Reaction
650 0 4 _aReceptor, Notch1
_xphysiology
650 0 4 _aReverse Transcriptase Polymerase Chain Reaction
650 0 4 _aSignal Transduction
650 0 4 _aThymocytes
650 0 4 _aZebrafish
_xgenetics
700 1 _aLiu, S
700 1 _aRaiser, D M
700 1 _aMartinez, S A
700 1 _aFeng, H
700 1 _aMeeker, N D
700 1 _aGentry, J
700 1 _aNeuberg, D
700 1 _aLook, A T
700 1 _aRamaswamy, S
700 1 _aBernards, A
700 1 _aTrede, N S
700 1 _aLangenau, D M
773 0 _tLeukemia
_gvol. 26
_gno. 9
_gp. 2069-78
856 4 0 _uhttps://doi.org/10.1038/leu.2012.116
_zAvailable from publisher's website
999 _c21736300
_d21736300