000 02399 a2200649 4500
005 20250516083909.0
264 0 _c20120828
008 201208s 0 0 eng d
022 _a1745-7254
024 7 _a10.1038/aps.2012.3
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aXu, Min-fang
245 0 0 _aAsiatic acid, a pentacyclic triterpene in Centella asiatica, attenuates glutamate-induced cognitive deficits in mice and apoptosis in SH-SY5Y cells.
_h[electronic resource]
260 _bActa pharmacologica Sinica
_cMay 2012
300 _a578-87 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAnimals, Newborn
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBehavior, Animal
_xdrug effects
650 0 4 _aBlotting, Western
650 0 4 _aCA1 Region, Hippocampal
_xdrug effects
650 0 4 _aCA3 Region, Hippocampal
_xdrug effects
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aCentella
_xchemistry
650 0 4 _aCognition
_xdrug effects
650 0 4 _aDementia
_xchemically induced
650 0 4 _aDisease Models, Animal
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aFlow Cytometry
650 0 4 _aGlutathione
_xmetabolism
650 0 4 _aHeat-Shock Proteins
_xmetabolism
650 0 4 _aHumans
650 0 4 _aLipid Peroxidation
_xdrug effects
650 0 4 _aMembrane Potential, Mitochondrial
_xdrug effects
650 0 4 _aMemory
_xdrug effects
650 0 4 _aMice
650 0 4 _aNeuroblastoma
_xmetabolism
650 0 4 _aNeuroprotective Agents
_xisolation & purification
650 0 4 _aNootropic Agents
_xisolation & purification
650 0 4 _aOxidative Stress
_xdrug effects
650 0 4 _aPentacyclic Triterpenes
_xisolation & purification
650 0 4 _aPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
650 0 4 _aSirtuin 1
_xmetabolism
650 0 4 _aSodium Glutamate
650 0 4 _aSuperoxide Dismutase
_xmetabolism
650 0 4 _aTime Factors
650 0 4 _aTranscription Factors
_xmetabolism
700 1 _aXiong, Yu-yun
700 1 _aLiu, Jian-kang
700 1 _aQian, Jin-jun
700 1 _aZhu, Li
700 1 _aGao, Jing
773 0 _tActa pharmacologica Sinica
_gvol. 33
_gno. 5
_gp. 578-87
856 4 0 _uhttps://doi.org/10.1038/aps.2012.3
_zAvailable from publisher's website
999 _c21650775
_d21650775