000 02058 a2200505 4500
005 20250516083004.0
264 0 _c20130104
008 201301s 0 0 eng d
022 _a1551-4005
024 7 _a10.4161/cc.19798
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSikka, Arron
245 0 0 _aMetformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation.
_h[electronic resource]
260 _bCell cycle (Georgetown, Tex.)
_cApr 2012
300 _a1374-82 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural
650 0 4 _aCarcinoma, Squamous Cell
_xdrug therapy
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCyclin D1
_xmetabolism
650 0 4 _aCyclin E
_xanalysis
650 0 4 _aCyclin-Dependent Kinase 2
_xmetabolism
650 0 4 _aCyclin-Dependent Kinase 4
_xmetabolism
650 0 4 _aCyclin-Dependent Kinase 6
_xmetabolism
650 0 4 _aCyclin-Dependent Kinase Inhibitor p15
_xmetabolism
650 0 4 _aCyclin-Dependent Kinase Inhibitor p16
650 0 4 _aCyclin-Dependent Kinase Inhibitor p18
_xmetabolism
650 0 4 _aCyclin-Dependent Kinase Inhibitor p27
_xmetabolism
650 0 4 _aG1 Phase Cell Cycle Checkpoints
_xdrug effects
650 0 4 _aHead and Neck Neoplasms
_xdrug therapy
650 0 4 _aHumans
650 0 4 _aMetformin
_xpharmacology
650 0 4 _aNeoplasm Proteins
_xmetabolism
650 0 4 _aProtein Biosynthesis
_xdrug effects
650 0 4 _aS-Phase Kinase-Associated Proteins
_xmetabolism
650 0 4 _aSquamous Cell Carcinoma of Head and Neck
650 0 4 _abeta-Transducin Repeat-Containing Proteins
_xmetabolism
650 0 4 _arho GTP-Binding Proteins
_xmetabolism
700 1 _aKaur, Manjinder
700 1 _aAgarwal, Chapla
700 1 _aDeep, Gagan
700 1 _aAgarwal, Rajesh
773 0 _tCell cycle (Georgetown, Tex.)
_gvol. 11
_gno. 7
_gp. 1374-82
856 4 0 _uhttps://doi.org/10.4161/cc.19798
_zAvailable from publisher's website
999 _c21625905
_d21625905