000 01752 a2200517 4500
005 20250516082246.0
264 0 _c20121226
008 201212s 0 0 eng d
022 _a1432-1041
024 7 _a10.1007/s00228-012-1248-z
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHelldén, A
245 0 0 _aThe dopaminergic stabilizer pridopidine is to a major extent N-depropylated by CYP2D6 in humans.
_h[electronic resource]
260 _bEuropean journal of clinical pharmacology
_cSep 2012
300 _a1281-6 p.
_bdigital
500 _aPublication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdministration, Oral
650 0 4 _aAdult
650 0 4 _aArea Under Curve
650 0 4 _aBiotransformation
650 0 4 _aCytochrome P-450 CYP2D6
_xmetabolism
650 0 4 _aCytochrome P-450 CYP2D6 Inhibitors
650 0 4 _aDealkylation
650 0 4 _aDopamine Antagonists
_xadministration & dosage
650 0 4 _aEnzyme Inhibitors
_xpharmacokinetics
650 0 4 _aGlomerular Filtration Rate
650 0 4 _aHalf-Life
650 0 4 _aHumans
650 0 4 _aIntestinal Absorption
650 0 4 _aKidney
_xmetabolism
650 0 4 _aMetabolic Clearance Rate
650 0 4 _aMiddle Aged
650 0 4 _aPhenotype
650 0 4 _aPiperidines
_xadministration & dosage
650 0 4 _aSweden
650 0 4 _aWhite People
650 0 4 _aYoung Adult
700 1 _aPanagiotidis, G
700 1 _aJohansson, P
700 1 _aWaters, N
700 1 _aWaters, S
700 1 _aTedroff, J
700 1 _aBertilsson, L
773 0 _tEuropean journal of clinical pharmacology
_gvol. 68
_gno. 9
_gp. 1281-6
856 4 0 _uhttps://doi.org/10.1007/s00228-012-1248-z
_zAvailable from publisher's website
999 _c21604844
_d21604844