| 000 | 01821 a2200517 4500 | ||
|---|---|---|---|
| 005 | 20250516082156.0 | ||
| 264 | 0 | _c20120904 | |
| 008 | 201209s 0 0 eng d | ||
| 022 | _a1553-7404 | ||
| 024 | 7 |
_a10.1371/journal.pgen.1002557 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aKrenzlin, Harald | |
| 245 | 0 | 0 |
_aDNA damage in Nijmegen Breakage Syndrome cells leads to PARP hyperactivation and increased oxidative stress. _h[electronic resource] |
| 260 |
_bPLoS genetics _c2012 |
||
| 300 |
_ae1002557 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aBleomycin _xpharmacology |
| 650 | 0 | 4 |
_aCell Cycle Proteins _xgenetics |
| 650 | 0 | 4 | _aCells, Cultured |
| 650 | 0 | 4 | _aDNA Breaks, Double-Stranded |
| 650 | 0 | 4 |
_aDNA Damage _xdrug effects |
| 650 | 0 | 4 | _aDNA-Binding Proteins |
| 650 | 0 | 4 | _aGene Expression Regulation |
| 650 | 0 | 4 | _aGene Knockdown Techniques |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aMice, Mutant Strains |
| 650 | 0 | 4 |
_aNAD _xmetabolism |
| 650 | 0 | 4 |
_aNijmegen Breakage Syndrome _xgenetics |
| 650 | 0 | 4 |
_aNuclear Proteins _xgenetics |
| 650 | 0 | 4 |
_aOxidative Stress _xdrug effects |
| 650 | 0 | 4 | _aPoly (ADP-Ribose) Polymerase-1 |
| 650 | 0 | 4 | _aPoly(ADP-ribose) Polymerase Inhibitors |
| 650 | 0 | 4 |
_aPoly(ADP-ribose) Polymerases _xgenetics |
| 650 | 0 | 4 |
_aReactive Oxygen Species _xmetabolism |
| 650 | 0 | 4 | _aTranscriptional Activation |
| 700 | 1 | _aDemuth, Ilja | |
| 700 | 1 | _aSalewsky, Bastian | |
| 700 | 1 | _aWessendorf, Petra | |
| 700 | 1 | _aWeidele, Kathrin | |
| 700 | 1 | _aBürkle, Alexander | |
| 700 | 1 | _aDigweed, Martin | |
| 773 | 0 |
_tPLoS genetics _gvol. 8 _gno. 3 _gp. e1002557 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1371/journal.pgen.1002557 _zAvailable from publisher's website |
| 999 |
_c21602438 _d21602438 |
||