000 02124 a2200613 4500
005 20250516081730.0
264 0 _c20120827
008 201208s 0 0 eng d
022 _a1932-6203
024 7 _a10.1371/journal.pone.0031046
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSampson, John H
245 0 0 _aA pilot study of IL-2Rα blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma.
_h[electronic resource]
260 _bPloS one
_c2012
300 _ae31046 p.
_bdigital
500 _aPublication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAntibodies, Monoclonal, Humanized
_xpharmacology
650 0 4 _aBrain Neoplasms
_xmetabolism
650 0 4 _aCD4-Positive T-Lymphocytes
_xcytology
650 0 4 _aCD8-Positive T-Lymphocytes
_xcytology
650 0 4 _aDaclizumab
650 0 4 _aFemale
650 0 4 _aGlioblastoma
_xmetabolism
650 0 4 _aHumans
650 0 4 _aImmune System
650 0 4 _aImmunoglobulin G
_xpharmacology
650 0 4 _aImmunosuppressive Agents
_xpharmacology
650 0 4 _aInterleukin-2 Receptor alpha Subunit
_xantagonists & inhibitors
650 0 4 _aLymphopenia
_xmetabolism
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aPilot Projects
650 0 4 _aT-Lymphocytes
_xcytology
650 0 4 _aT-Lymphocytes, Regulatory
_xmetabolism
700 1 _aSchmittling, Robert J
700 1 _aArcher, Gary E
700 1 _aCongdon, Kendra L
700 1 _aNair, Smita K
700 1 _aReap, Elizabeth A
700 1 _aDesjardins, Annick
700 1 _aFriedman, Allan H
700 1 _aFriedman, Henry S
700 1 _aHerndon, James E
700 1 _aCoan, April
700 1 _aMcLendon, Roger E
700 1 _aReardon, David A
700 1 _aVredenburgh, James J
700 1 _aBigner, Darell D
700 1 _aMitchell, Duane A
773 0 _tPloS one
_gvol. 7
_gno. 2
_gp. e31046
856 4 0 _uhttps://doi.org/10.1371/journal.pone.0031046
_zAvailable from publisher's website
999 _c21591071
_d21591071