000 01875 a2200529 4500
005 20250516081451.0
264 0 _c20130429
008 201304s 0 0 eng d
022 _a1522-9645
024 7 _a10.1093/eurheartj/ehs042
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aGong, Inna Y
245 0 0 _aClarifying the importance of CYP2C19 and PON1 in the mechanism of clopidogrel bioactivation and in vivo antiplatelet response.
_h[electronic resource]
260 _bEuropean heart journal
_cNov 2012
300 _a2856-2464a p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdolescent
650 0 4 _aAdult
650 0 4 _aArea Under Curve
650 0 4 _aAryl Hydrocarbon Hydroxylases
_xgenetics
650 0 4 _aAryldialkylphosphatase
_xgenetics
650 0 4 _aBiotransformation
_xdrug effects
650 0 4 _aClopidogrel
650 0 4 _aCytochrome P-450 CYP2C19
650 0 4 _aCytochrome P-450 CYP3A
_xdrug effects
650 0 4 _aEnzyme Inhibitors
_xpharmacokinetics
650 0 4 _aHumans
650 0 4 _aMidazolam
_xpharmacokinetics
650 0 4 _aMiddle Aged
650 0 4 _aPlatelet Aggregation
_xdrug effects
650 0 4 _aPlatelet Aggregation Inhibitors
_xpharmacokinetics
650 0 4 _aPolymorphism, Genetic
_xgenetics
650 0 4 _aTiclopidine
_xanalogs & derivatives
650 0 4 _aYoung Adult
700 1 _aCrown, Natalie
700 1 _aSuen, Colin M
700 1 _aSchwarz, Ute I
700 1 _aDresser, George K
700 1 _aKnauer, Michael J
700 1 _aSugiyama, Daisuke
700 1 _aDeGorter, Marianne K
700 1 _aWoolsey, Sarah
700 1 _aTirona, Rommel G
700 1 _aKim, Richard B
773 0 _tEuropean heart journal
_gvol. 33
_gno. 22
_gp. 2856-2464a
856 4 0 _uhttps://doi.org/10.1093/eurheartj/ehs042
_zAvailable from publisher's website
999 _c21583224
_d21583224