000 01947 a2200553 4500
005 20250516081116.0
264 0 _c20120629
008 201206s 0 0 eng d
022 _a1932-6203
024 7 _a10.1371/journal.pone.0031839
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aForbes, Nicole E
245 0 0 _aMultifunctional adaptive NS1 mutations are selected upon human influenza virus evolution in the mouse.
_h[electronic resource]
260 _bPloS one
_c2012
300 _ae31839 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAdaptation, Biological
_xdrug effects
650 0 4 _aAnimals
650 0 4 _aBiological Assay
650 0 4 _aGene Expression Regulation, Viral
_xdrug effects
650 0 4 _aHalf-Life
650 0 4 _aHost Specificity
_xdrug effects
650 0 4 _aHumans
650 0 4 _aInfluenza A virus
_xdrug effects
650 0 4 _aInfluenza, Human
_xvirology
650 0 4 _aInterferon-beta
_xbiosynthesis
650 0 4 _aLung
_xdrug effects
650 0 4 _aMice
650 0 4 _aMolecular Sequence Data
650 0 4 _aMutant Proteins
_xmetabolism
650 0 4 _aMutation
_xgenetics
650 0 4 _aOrthomyxoviridae Infections
_xpathology
650 0 4 _aProtein Binding
_xdrug effects
650 0 4 _aProtein Biosynthesis
_xdrug effects
650 0 4 _aRNA, Messenger
_xgenetics
650 0 4 _aRecombination, Genetic
_xgenetics
650 0 4 _aSelection, Genetic
650 0 4 _aViral Nonstructural Proteins
_xgenetics
650 0 4 _aVirulence
_xdrug effects
700 1 _aPing, Jihui
700 1 _aDankar, Samar K
700 1 _aJia, Jian-Jun
700 1 _aSelman, Mohammed
700 1 _aKeleta, Liya
700 1 _aZhou, Yan
700 1 _aBrown, Earl G
773 0 _tPloS one
_gvol. 7
_gno. 2
_gp. e31839
856 4 0 _uhttps://doi.org/10.1371/journal.pone.0031839
_zAvailable from publisher's website
999 _c21572827
_d21572827