000 03188 a2200985 4500
005 20250516080807.0
264 0 _c20120717
008 201207s 0 0 eng d
022 _a1449-2288
024 7 _a10.7150/ijbs.3524
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aZhang, Liwen
245 0 0 _aAn anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes.
_h[electronic resource]
260 _bInternational journal of biological sciences
_c2012
300 _a310-27 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnimals
650 0 4 _aAntibodies, Monoclonal
_xpharmacology
650 0 4 _aAntibody Affinity
650 0 4 _aAnticholesteremic Agents
_xadministration & dosage
650 0 4 _aCells, Cultured
_xdrug effects
650 0 4 _aCholesterol Ester Transfer Proteins
_xgenetics
650 0 4 _aCholesterol, LDL
_xblood
650 0 4 _aGene Expression Profiling
650 0 4 _aGene Expression Regulation
_xdrug effects
650 0 4 _aHep G2 Cells
_xdrug effects
650 0 4 _aHepatocytes
_xdrug effects
650 0 4 _aHumans
650 0 4 _aImmunization, Passive
650 0 4 _aLipid Metabolism
_xgenetics
650 0 4 _aLiver
_xdrug effects
650 0 4 _aMacaca mulatta
650 0 4 _aMetabolic Syndrome
_xdrug therapy
650 0 4 _aMice
650 0 4 _aMice, Transgenic
650 0 4 _aProprotein Convertase 9
650 0 4 _aProprotein Convertases
_xantagonists & inhibitors
650 0 4 _aRNA, Messenger
_xmetabolism
650 0 4 _aReceptors, LDL
_xbiosynthesis
650 0 4 _aRecombinant Proteins
_xmetabolism
650 0 4 _aSerine Endopeptidases
_xbiosynthesis
650 0 4 _aSimvastatin
_xadministration & dosage
650 0 4 _aSterol Regulatory Element Binding Proteins
_xphysiology
700 1 _aMcCabe, Timothy
700 1 _aCondra, Jon H
700 1 _aNi, Yan G
700 1 _aPeterson, Laurence B
700 1 _aWang, Weirong
700 1 _aStrack, Alison M
700 1 _aWang, Fubao
700 1 _aPandit, Shilpa
700 1 _aHammond, Holly
700 1 _aWood, Dana
700 1 _aLewis, Dale
700 1 _aRosa, Ray
700 1 _aMendoza, Vivienne
700 1 _aCumiskey, Anne Marie
700 1 _aJohns, Douglas G
700 1 _aHansen, Barbara C
700 1 _aShen, Xun
700 1 _aGeoghagen, Neil
700 1 _aJensen, Kristian
700 1 _aZhu, Lei
700 1 _aWietecha, Karol
700 1 _aWisniewski, Douglas
700 1 _aHuang, Lingyi
700 1 _aZhao, Jing Zhang
700 1 _aErnst, Robin
700 1 _aHampton, Richard
700 1 _aHaytko, Peter
700 1 _aAnsbro, Frances
700 1 _aChilewski, Shannon
700 1 _aChin, Jayne
700 1 _aMitnaul, Lyndon J
700 1 _aPellacani, Andrea
700 1 _aSparrow, Carl P
700 1 _aAn, Zhiqiang
700 1 _aStrohl, William
700 1 _aHubbard, Brian
700 1 _aPlump, Andrew S
700 1 _aBlom, Daniel
700 1 _aSitlani, Ayesha
773 0 _tInternational journal of biological sciences
_gvol. 8
_gno. 3
_gp. 310-27
856 4 0 _uhttps://doi.org/10.7150/ijbs.3524
_zAvailable from publisher's website
999 _c21564761
_d21564761