000 02119 a2200577 4500
005 20250516080708.0
264 0 _c20120508
008 201205s 0 0 eng d
022 _a1540-9538
024 7 _a10.1084/jem.20111923
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aCook, Natalie
245 0 0 _aGamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma.
_h[electronic resource]
260 _bThe Journal of experimental medicine
_cMar 2012
300 _a437-44 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAmyloid Precursor Protein Secretases
_xantagonists & inhibitors
650 0 4 _aAnimals
650 0 4 _aCarcinoma, Pancreatic Ductal
_xblood supply
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCyclic S-Oxides
_xadministration & dosage
650 0 4 _aDeoxycytidine
_xadministration & dosage
650 0 4 _aDrug Synergism
650 0 4 _aDrug Therapy, Combination
650 0 4 _aEndothelial Cells
_xdrug effects
650 0 4 _aHumans
650 0 4 _aHypoxia
_xchemically induced
650 0 4 _aMice
650 0 4 _aMice, Mutant Strains
650 0 4 _aNecrosis
650 0 4 _aPancreatic Neoplasms
_xblood supply
650 0 4 _aProtease Inhibitors
_xadministration & dosage
650 0 4 _aReceptors, Notch
_xmetabolism
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aThiadiazoles
_xadministration & dosage
650 0 4 _aTranslational Research, Biomedical
650 0 4 _aGemcitabine
700 1 _aFrese, Kristopher K
700 1 _aBapiro, Tashinga E
700 1 _aJacobetz, Michael A
700 1 _aGopinathan, Aarthi
700 1 _aMiller, Jodi L
700 1 _aRao, Sudhir S
700 1 _aDemuth, Tim
700 1 _aHowat, William J
700 1 _aJodrell, Duncan I
700 1 _aTuveson, David A
773 0 _tThe Journal of experimental medicine
_gvol. 209
_gno. 3
_gp. 437-44
856 4 0 _uhttps://doi.org/10.1084/jem.20111923
_zAvailable from publisher's website
999 _c21561755
_d21561755