| 000 | 02502 a2200757 4500 | ||
|---|---|---|---|
| 005 | 20250516075529.0 | ||
| 264 | 0 | _c20120823 | |
| 008 | 201208s 0 0 eng d | ||
| 022 | _a1521-009X | ||
| 024 | 7 |
_a10.1124/dmd.111.043778 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aChoo, Edna F | |
| 245 | 0 | 0 |
_aPreclinical disposition of GDC-0973 and prospective and retrospective analysis of human dose and efficacy predictions. _h[electronic resource] |
| 260 |
_bDrug metabolism and disposition: the biological fate of chemicals _cMay 2012 |
||
| 300 |
_a919-27 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAdministration, Oral |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aAntineoplastic Agents _xadministration & dosage |
| 650 | 0 | 4 | _aAutoradiography |
| 650 | 0 | 4 |
_aAzetidines _xadministration & dosage |
| 650 | 0 | 4 |
_aBile _xmetabolism |
| 650 | 0 | 4 |
_aBrain _xmetabolism |
| 650 | 0 | 4 | _aCell Line, Tumor |
| 650 | 0 | 4 |
_aCell Membrane _xmetabolism |
| 650 | 0 | 4 | _aCell Membrane Permeability |
| 650 | 0 | 4 |
_aColorectal Neoplasms _xdrug therapy |
| 650 | 0 | 4 | _aDogs |
| 650 | 0 | 4 | _aDose-Response Relationship, Drug |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aInjections, Intravenous |
| 650 | 0 | 4 | _aMacaca fascicularis |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aMice, Nude |
| 650 | 0 | 4 |
_aMicrosomes, Liver _xmetabolism |
| 650 | 0 | 4 | _aModels, Biological |
| 650 | 0 | 4 |
_aPiperidines _xadministration & dosage |
| 650 | 0 | 4 | _aPredictive Value of Tests |
| 650 | 0 | 4 | _aProspective Studies |
| 650 | 0 | 4 |
_aProtein Kinase Inhibitors _xadministration & dosage |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 | _aRats, Long-Evans |
| 650 | 0 | 4 | _aRats, Sprague-Dawley |
| 650 | 0 | 4 | _aRetrospective Studies |
| 650 | 0 | 4 | _aSpecies Specificity |
| 650 | 0 | 4 | _aTissue Distribution |
| 650 | 0 | 4 | _aXenograft Model Antitumor Assays |
| 700 | 1 | _aBelvin, Marcia | |
| 700 | 1 | _aBoggs, Jason | |
| 700 | 1 | _aDeng, Yuzhong | |
| 700 | 1 | _aHoeflich, Klaus P | |
| 700 | 1 | _aLy, Justin | |
| 700 | 1 | _aMerchant, Mark | |
| 700 | 1 | _aOrr, Christine | |
| 700 | 1 | _aPlise, Emile | |
| 700 | 1 | _aRobarge, Kirk | |
| 700 | 1 | _aMartini, Jean F | |
| 700 | 1 | _aKassees, Robert | |
| 700 | 1 | _aAoyama, Ron G | |
| 700 | 1 | _aRamaiya, Atulkumar | |
| 700 | 1 | _aJohnston, Stuart H | |
| 773 | 0 |
_tDrug metabolism and disposition: the biological fate of chemicals _gvol. 40 _gno. 5 _gp. 919-27 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1124/dmd.111.043778 _zAvailable from publisher's website |
| 999 |
_c21527393 _d21527393 |
||