000			02168 a2200637 4500
005			20250516074430.0
264		0	_c20120418
008			201204s 0 0 eng d
022			_a1476-4687
024	7		_a10.1038/nature10868 _2doi
040			_aNLM _beng _cNLM
100	1		_aPrahallad, Anirudh
245	0	0	_aUnresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR. _h[electronic resource]
260			_bNature _cJan 2012
300			_a100-3 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAnimals
650	0	4	_aAntibodies, Monoclonal _xpharmacology
650	0	4	_aAntibodies, Monoclonal, Humanized
650	0	4	_aAntineoplastic Agents _xpharmacology
650	0	4	_aApoptosis _xdrug effects
650	0	4	_aCell Line, Tumor
650	0	4	_aCell Proliferation _xdrug effects
650	0	4	_aCetuximab
650	0	4	_aColorectal Neoplasms _xdrug therapy
650	0	4	_aDrug Resistance, Neoplasm _xdrug effects
650	0	4	_aDrug Synergism
650	0	4	_aEnzyme Activation _xdrug effects
650	0	4	_aErbB Receptors _xagonists
650	0	4	_aErlotinib Hydrochloride
650	0	4	_aFeedback, Physiological _xdrug effects
650	0	4	_aFemale
650	0	4	_aGefitinib
650	0	4	_aHEK293 Cells
650	0	4	_aHumans
650	0	4	_aIndoles _xpharmacology
650	0	4	_aMelanoma _xdrug therapy
650	0	4	_aMice
650	0	4	_aProtein Kinase Inhibitors _xpharmacology
650	0	4	_aProto-Oncogene Proteins B-raf _xantagonists & inhibitors
650	0	4	_aQuinazolines _xpharmacology
650	0	4	_aRNA Interference
650	0	4	_aSulfonamides _xpharmacology
650	0	4	_aVemurafenib
650	0	4	_aXenograft Model Antitumor Assays
700	1		_aSun, Chong
700	1		_aHuang, Sidong
700	1		_aDi Nicolantonio, Federica
700	1		_aSalazar, Ramon
700	1		_aZecchin, Davide
700	1		_aBeijersbergen, Roderick L
700	1		_aBardelli, Alberto
700	1		_aBernards, René
773	0		_tNature _gvol. 483 _gno. 7387 _gp. 100-3
856	4	0	_uhttps://doi.org/10.1038/nature10868 _zAvailable from publisher's website
999			_c21495359 _d21495359