000 01762 a2200493 4500
005 20250516074317.0
264 0 _c20130603
008 201306s 0 0 eng d
022 _a1880-0920
024 7 _a10.2133/dmpk.dmpk-11-rg-134
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aTakashina, Yoshiaki
245 0 0 _aImpact of CYP3A5 and ABCB1 gene polymorphisms on fentanyl pharmacokinetics and clinical responses in cancer patients undergoing conversion to a transdermal system.
_h[electronic resource]
260 _bDrug metabolism and pharmacokinetics
_c2012
300 _a414-21 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aATP Binding Cassette Transporter, Subfamily B
650 0 4 _aATP Binding Cassette Transporter, Subfamily B, Member 1
_xgenetics
650 0 4 _aAdministration, Cutaneous
650 0 4 _aAged
650 0 4 _aAnalgesics, Opioid
_xadministration & dosage
650 0 4 _aCytochrome P-450 CYP3A
_xgenetics
650 0 4 _aDrug Monitoring
650 0 4 _aFemale
650 0 4 _aFentanyl
_xadministration & dosage
650 0 4 _aGenotype
650 0 4 _aHumans
650 0 4 _aJapan
650 0 4 _aLogistic Models
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aNeoplasms
_xdrug therapy
650 0 4 _aOdds Ratio
650 0 4 _aPharmacogenetics
650 0 4 _aPhenotype
650 0 4 _aPolymorphism, Genetic
700 1 _aNaito, Takafumi
700 1 _aMino, Yasuaki
700 1 _aYagi, Tatsuya
700 1 _aOhnishi, Kazunori
700 1 _aKawakami, Junichi
773 0 _tDrug metabolism and pharmacokinetics
_gvol. 27
_gno. 4
_gp. 414-21
856 4 0 _uhttps://doi.org/10.2133/dmpk.dmpk-11-rg-134
_zAvailable from publisher's website
999 _c21491623
_d21491623