000 01597 a2200421 4500
005 20250516073818.0
264 0 _c20120504
008 201205s 0 0 eng d
022 _a1521-0103
024 7 _a10.1124/jpet.111.190173
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aZhou, Xin
245 0 0 _aRole of CYP2A5 in the bioactivation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice.
_h[electronic resource]
260 _bThe Journal of pharmacology and experimental therapeutics
_cApr 2012
300 _a233-41 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural
650 0 4 _aAdenocarcinoma
_xchemically induced
650 0 4 _aAdenocarcinoma of Lung
650 0 4 _aAnimals
650 0 4 _aAryl Hydrocarbon Hydroxylases
_xdeficiency
650 0 4 _aBiotransformation
_xdrug effects
650 0 4 _aCytochrome P-450 CYP2A6
650 0 4 _aCytochrome P450 Family 2
650 0 4 _aFemale
650 0 4 _aLung
_xdrug effects
650 0 4 _aLung Neoplasms
_xchemically induced
650 0 4 _aMice
650 0 4 _aMice, Knockout
650 0 4 _aMicrosomes, Liver
_xdrug effects
650 0 4 _aNitrosamines
_xmetabolism
650 0 4 _aPyridines
_xmetabolism
650 0 4 _aTissue Distribution
_xdrug effects
700 1 _aD'Agostino, Jaime
700 1 _aXie, Fang
700 1 _aDing, Xinxin
773 0 _tThe Journal of pharmacology and experimental therapeutics
_gvol. 341
_gno. 1
_gp. 233-41
856 4 0 _uhttps://doi.org/10.1124/jpet.111.190173
_zAvailable from publisher's website
999 _c21477988
_d21477988