000 02038 a2200565 4500
005 20250516073358.0
264 0 _c20121213
008 201212s 0 0 eng d
022 _a1476-5594
024 7 _a10.1038/onc.2011.617
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aAstanehe, A
245 0 0 _aMKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition.
_h[electronic resource]
260 _bOncogene
_cOct 2012
300 _a4434-46 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAntibodies, Monoclonal, Humanized
_xpharmacology
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aApoptosis
650 0 4 _aBase Sequence
650 0 4 _aBreast Neoplasms
_xdrug therapy
650 0 4 _aCell Line, Tumor
650 0 4 _aChromatin Immunoprecipitation
650 0 4 _aDrug Resistance, Neoplasm
_xgenetics
650 0 4 _aFemale
650 0 4 _aGene Expression Regulation, Neoplastic
650 0 4 _aGene Knockdown Techniques
650 0 4 _aHumans
650 0 4 _aIntracellular Signaling Peptides and Proteins
_xgenetics
650 0 4 _aPhosphorylation
650 0 4 _aProtein Array Analysis
650 0 4 _aProtein Processing, Post-Translational
650 0 4 _aProtein Serine-Threonine Kinases
_xgenetics
650 0 4 _aPteridines
_xpharmacology
650 0 4 _aRibosomal Protein S6 Kinases, 90-kDa
_xantagonists & inhibitors
650 0 4 _aSequence Analysis, DNA
650 0 4 _aTranscription, Genetic
650 0 4 _aTrastuzumab
650 0 4 _aY-Box-Binding Protein 1
_xmetabolism
700 1 _aFinkbeiner, M R
700 1 _aKrzywinski, M
700 1 _aFotovati, A
700 1 _aDhillon, J
700 1 _aBerquin, I M
700 1 _aMills, G B
700 1 _aMarra, M A
700 1 _aDunn, S E
773 0 _tOncogene
_gvol. 31
_gno. 41
_gp. 4434-46
856 4 0 _uhttps://doi.org/10.1038/onc.2011.617
_zAvailable from publisher's website
999 _c21464948
_d21464948