000 01799 a2200505 4500
005 20250516073328.0
264 0 _c20120514
008 201205s 0 0 eng d
022 _a1932-6203
024 7 _a10.1371/journal.pone.0028899
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKeravis, Thérèse
245 0 0 _aDisease progression in MRL/lpr lupus-prone mice is reduced by NCS 613, a specific cyclic nucleotide phosphodiesterase type 4 (PDE4) inhibitor.
_h[electronic resource]
260 _bPloS one
_c2012
300 _ae28899 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdenine
_xanalogs & derivatives
650 0 4 _aAnimals
650 0 4 _aCyclic AMP
_xmetabolism
650 0 4 _aCyclic Nucleotide Phosphodiesterases, Type 4
_xchemistry
650 0 4 _aDisease Progression
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aIsoenzymes
650 0 4 _aKidney
_xcytology
650 0 4 _aLipopolysaccharides
_xpharmacology
650 0 4 _aLupus Erythematosus, Systemic
_xdrug therapy
650 0 4 _aMice
650 0 4 _aMice, Inbred CBA
650 0 4 _aMice, Inbred MRL lpr
650 0 4 _aPentoxifylline
_xtherapeutic use
650 0 4 _aPhosphodiesterase 4 Inhibitors
_xtherapeutic use
650 0 4 _aProteinuria
_xdrug therapy
650 0 4 _aSurvival Rate
650 0 4 _aTumor Necrosis Factor-alpha
_xmetabolism
650 0 4 _aXanthines
_xtherapeutic use
700 1 _aMonneaux, Fanny
700 1 _aYougbaré, Issaka
700 1 _aGazi, Lucien
700 1 _aBourguignon, Jean-Jacques
700 1 _aMuller, Sylviane
700 1 _aLugnier, Claire
773 0 _tPloS one
_gvol. 7
_gno. 1
_gp. e28899
856 4 0 _uhttps://doi.org/10.1371/journal.pone.0028899
_zAvailable from publisher's website
999 _c21463531
_d21463531