000 02597 a2200637 4500
005 20250516073110.0
264 0 _c20120612
008 201206s 0 0 eng d
022 _a1873-2399
024 7 _a10.1016/j.exphem.2012.01.004
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aAiriau, Kelly
245 0 0 _aABT-737 increases tyrosine kinase inhibitor-induced apoptosis in chronic myeloid leukemia cells through XIAP downregulation and sensitizes CD34(+) CD38(-) population to imatinib.
_h[electronic resource]
260 _bExperimental hematology
_cMay 2012
300 _a367-78.e2 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntigens, CD34
_xanalysis
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aApoptosis Regulatory Proteins
_xphysiology
650 0 4 _aBcl-2-Like Protein 11
650 0 4 _aBenzamides
650 0 4 _aBiphenyl Compounds
_xpharmacology
650 0 4 _aCell Line, Tumor
_xdrug effects
650 0 4 _aDown-Regulation
_xdrug effects
650 0 4 _aDrug Resistance, Neoplasm
_xdrug effects
650 0 4 _aDrug Screening Assays, Antitumor
650 0 4 _aDrug Synergism
650 0 4 _aGene Expression Regulation, Leukemic
_xdrug effects
650 0 4 _aHematopoietic Stem Cells
_xdrug effects
650 0 4 _aHigh-Temperature Requirement A Serine Peptidase 2
650 0 4 _aHumans
650 0 4 _aImatinib Mesylate
650 0 4 _aK562 Cells
_xdrug effects
650 0 4 _aLeukemia, Myelogenous, Chronic, BCR-ABL Positive
_xpathology
650 0 4 _aMembrane Proteins
_xphysiology
650 0 4 _aMitochondrial Proteins
_xphysiology
650 0 4 _aNeoplasm Proteins
_xbiosynthesis
650 0 4 _aNeoplastic Stem Cells
_xdrug effects
650 0 4 _aNitrophenols
_xpharmacology
650 0 4 _aPiperazines
_xpharmacology
650 0 4 _aProtein Kinase Inhibitors
_xpharmacology
650 0 4 _aProto-Oncogene Proteins
_xphysiology
650 0 4 _aProto-Oncogene Proteins c-bcl-2
_xantagonists & inhibitors
650 0 4 _aPyrimidines
_xpharmacology
650 0 4 _aSerine Endopeptidases
_xphysiology
650 0 4 _aSulfonamides
_xpharmacology
650 0 4 _aX-Linked Inhibitor of Apoptosis Protein
_xbiosynthesis
700 1 _aMahon, François-Xavier
700 1 _aJosselin, Marina
700 1 _aJeanneteau, Marie
700 1 _aTurcq, Beatrice
700 1 _aBelloc, Francis
773 0 _tExperimental hematology
_gvol. 40
_gno. 5
_gp. 367-78.e2
856 4 0 _uhttps://doi.org/10.1016/j.exphem.2012.01.004
_zAvailable from publisher's website
999 _c21456952
_d21456952