000			01988 a2200565 4500
005			20250516072914.0
264		0	_c20120612
008			201206s 0 0 eng d
022			_a1528-0020
024	7		_a10.1182/blood-2011-06-359224 _2doi
040			_aNLM _beng _cNLM
100	1		_aPascale, Silvia
245	0	0	_aAspirin-insensitive thromboxane biosynthesis in essential thrombocythemia is explained by accelerated renewal of the drug target. _h[electronic resource]
260			_bBlood _cApr 2012
300			_a3595-603 p. _bdigital
500			_aPublication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
650	0	4	_aAcceleration
650	0	4	_aAdult
650	0	4	_aAged
650	0	4	_aAlgorithms
650	0	4	_aAnti-Inflammatory Agents, Non-Steroidal _xtherapeutic use
650	0	4	_aAspirin _xadministration & dosage
650	0	4	_aCross-Over Studies
650	0	4	_aCross-Sectional Studies _xstatistics & numerical data
650	0	4	_aCyclooxygenase 1 _xmetabolism
650	0	4	_aCyclooxygenase 2 _xmetabolism
650	0	4	_aDrug Resistance _xdrug effects
650	0	4	_aFemale
650	0	4	_aHalf-Life
650	0	4	_aHumans
650	0	4	_aMale
650	0	4	_aMetabolic Networks and Pathways _xdrug effects
650	0	4	_aMiddle Aged
650	0	4	_aMolecular Targeted Therapy _xmethods
650	0	4	_aProtein Biosynthesis _xdrug effects
650	0	4	_aThrombocythemia, Essential _xdrug therapy
650	0	4	_aThromboxane A2 _xbiosynthesis
700	1		_aPetrucci, Giovanna
700	1		_aDragani, Alfredo
700	1		_aHabib, Aida
700	1		_aZaccardi, Francesco
700	1		_aPagliaccia, Francesca
700	1		_aPocaterra, Davide
700	1		_aRagazzoni, Enzo
700	1		_aRolandi, Giancarlo
700	1		_aRocca, Bianca
700	1		_aPatrono, Carlo
773	0		_tBlood _gvol. 119 _gno. 15 _gp. 3595-603
856	4	0	_uhttps://doi.org/10.1182/blood-2011-06-359224 _zAvailable from publisher's website
999			_c21451363 _d21451363