000 01947 a2200553 4500
005 20250516072541.0
264 0 _c20120307
008 201203s 0 0 eng d
022 _a1520-4995
024 7 _a10.1021/bi201428h
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aTian, Wang
245 0 0 _aStructure-based discovery of a novel inhibitor targeting the β-catenin/Tcf4 interaction.
_h[electronic resource]
260 _bBiochemistry
_cJan 2012
300 _a724-31 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aBasic Helix-Loop-Helix Leucine Zipper Transcription Factors
_xchemistry
650 0 4 _aBasic Helix-Loop-Helix Transcription Factors
_xmetabolism
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aCrystallography, X-Ray
650 0 4 _aDown-Regulation
_xdrug effects
650 0 4 _aDrug Evaluation, Preclinical
_xmethods
650 0 4 _aHCT116 Cells
650 0 4 _aHumans
650 0 4 _aModels, Molecular
650 0 4 _aProtein Binding
_xdrug effects
650 0 4 _aProtein Conformation
650 0 4 _aSmall Molecule Libraries
_xpharmacology
650 0 4 _aTranscription Factor 4
650 0 4 _aTranscription Factors
_xchemistry
650 0 4 _aTranscription, Genetic
_xdrug effects
650 0 4 _aUser-Computer Interface
650 0 4 _aWnt Signaling Pathway
_xdrug effects
650 0 4 _abeta Catenin
_xchemistry
700 1 _aHan, Xiaofeng
700 1 _aYan, Maocai
700 1 _aXu, Yan
700 1 _aDuggineni, Srinivas
700 1 _aLin, Nan
700 1 _aLuo, Guifen
700 1 _aLi, Yan Michael
700 1 _aHan, Xiaobing
700 1 _aHuang, Ziwei
700 1 _aAn, Jing
773 0 _tBiochemistry
_gvol. 51
_gno. 2
_gp. 724-31
856 4 0 _uhttps://doi.org/10.1021/bi201428h
_zAvailable from publisher's website
999 _c21442030
_d21442030