000 02131 a2200589 4500
005 20250516071907.0
264 0 _c20120618
008 201206s 0 0 eng d
022 _a1538-8514
024 7 _a10.1158/1535-7163.MCT-11-0406
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMontano, Ryan
245 0 0 _aPreclinical development of the novel Chk1 inhibitor SCH900776 in combination with DNA-damaging agents and antimetabolites.
_h[electronic resource]
260 _bMolecular cancer therapeutics
_cFeb 2012
300 _a427-38 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural
650 0 4 _aAntimetabolites
_xpharmacology
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aBlotting, Western
650 0 4 _aCamptothecin
_xanalogs & derivatives
650 0 4 _aCell Cycle Checkpoints
_xdrug effects
650 0 4 _aCell Line
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aCheckpoint Kinase 1
650 0 4 _aCytarabine
_xpharmacology
650 0 4 _aDNA Breaks, Double-Stranded
_xdrug effects
650 0 4 _aDNA Damage
650 0 4 _aDeoxycytidine
_xanalogs & derivatives
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Screening Assays, Antitumor
650 0 4 _aDrug Synergism
650 0 4 _aFlow Cytometry
650 0 4 _aHumans
650 0 4 _aHydroxyurea
_xpharmacology
650 0 4 _aIrinotecan
650 0 4 _aMolecular Structure
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aProtein Kinase Inhibitors
_xchemistry
650 0 4 _aProtein Kinases
_xmetabolism
650 0 4 _aPyrazoles
_xchemistry
650 0 4 _aPyrimidines
_xchemistry
650 0 4 _aStaurosporine
_xanalogs & derivatives
650 0 4 _aGemcitabine
700 1 _aChung, Injae
700 1 _aGarner, Kristen M
700 1 _aParry, David
700 1 _aEastman, Alan
773 0 _tMolecular cancer therapeutics
_gvol. 11
_gno. 2
_gp. 427-38
856 4 0 _uhttps://doi.org/10.1158/1535-7163.MCT-11-0406
_zAvailable from publisher's website
999 _c21423111
_d21423111