000 02095 a2200589 4500
005 20250516071117.0
264 0 _c20120618
008 201206s 0 0 eng d
022 _a1538-8514
024 7 _a10.1158/1535-7163.MCT-11-0412
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aTai, Wei-Tien
245 0 0 _aDovitinib induces apoptosis and overcomes sorafenib resistance in hepatocellular carcinoma through SHP-1-mediated inhibition of STAT3.
_h[electronic resource]
260 _bMolecular cancer therapeutics
_cFeb 2012
300 _a452-63 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBenzenesulfonates
_xpharmacology
650 0 4 _aBenzimidazoles
_xchemistry
650 0 4 _aBlotting, Western
650 0 4 _aCarcinoma, Hepatocellular
_xdrug therapy
650 0 4 _aCell Line, Tumor
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Resistance, Neoplasm
_xdrug effects
650 0 4 _aHumans
650 0 4 _aLiver Neoplasms
_xdrug therapy
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Nude
650 0 4 _aMolecular Structure
650 0 4 _aNiacinamide
_xanalogs & derivatives
650 0 4 _aPhenylurea Compounds
650 0 4 _aProtein Kinase Inhibitors
_xchemistry
650 0 4 _aProtein Tyrosine Phosphatase, Non-Receptor Type 6
_xgenetics
650 0 4 _aPyridines
_xpharmacology
650 0 4 _aQuinolones
_xchemistry
650 0 4 _aRNA Interference
650 0 4 _aSTAT3 Transcription Factor
_xgenetics
650 0 4 _aSorafenib
650 0 4 _aTumor Burden
_xdrug effects
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aCheng, Ann-Lii
700 1 _aShiau, Chung-Wai
700 1 _aLiu, Chun-Yu
700 1 _aKo, Ching-Huai
700 1 _aLin, Mai-Wei
700 1 _aChen, Pei-Jer
700 1 _aChen, Kuen-Feng
773 0 _tMolecular cancer therapeutics
_gvol. 11
_gno. 2
_gp. 452-63
856 4 0 _uhttps://doi.org/10.1158/1535-7163.MCT-11-0412
_zAvailable from publisher's website
999 _c21401849
_d21401849