000 01706 a2200469 4500
005 20250516070355.0
264 0 _c20120816
008 201208s 0 0 eng d
022 _a1536-4828
024 7 _a10.1097/MPA.0b013e318239c6e5
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLee, Wing-Kee
245 0 0 _aCyclosporin a, but not FK506, induces osmotic lysis of pancreas zymogen granules, intra-acinar enzyme release, and lysosome instability by activating K+ channel.
_h[electronic resource]
260 _bPancreas
_cMay 2012
300 _a596-604 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAcinar Cells
_xdrug effects
650 0 4 _aAmylases
_xmetabolism
650 0 4 _aAnimals
650 0 4 _aBiomarkers
_xmetabolism
650 0 4 _aCathepsin B
_xmetabolism
650 0 4 _aCyclosporine
_xadverse effects
650 0 4 _aImmunosuppressive Agents
_xadverse effects
650 0 4 _aLysosomes
_xdrug effects
650 0 4 _aMale
650 0 4 _aOsmosis
_xdrug effects
650 0 4 _aPancreas
_xblood supply
650 0 4 _aPancreas Transplantation
650 0 4 _aPancreatitis, Graft
_xetiology
650 0 4 _aPermeability
_xdrug effects
650 0 4 _aPotassium Channels
_xdrug effects
650 0 4 _aRats
650 0 4 _aRats, Wistar
650 0 4 _aReperfusion Injury
_xetiology
650 0 4 _aSecretory Vesicles
_xdrug effects
650 0 4 _aTacrolimus
_xpharmacology
700 1 _aBraun, Matthias
700 1 _aLangelüddecke, Christian
700 1 _aThévenod, Frank
773 0 _tPancreas
_gvol. 41
_gno. 4
_gp. 596-604
856 4 0 _uhttps://doi.org/10.1097/MPA.0b013e318239c6e5
_zAvailable from publisher's website
999 _c21381166
_d21381166