000 01819 a2200541 4500
005 20250516070245.0
264 0 _c20120803
008 201208s 0 0 eng d
022 _a1464-3405
024 7 _a10.1016/j.bmcl.2011.11.071
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aStokes, Suzanne S
245 0 0 _aDiscovery of bacterial NAD⁺-dependent DNA ligase inhibitors: improvements in clearance of adenosine series.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cJan 2012
300 _a85-9 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAdenine
_xchemistry
650 0 4 _aAdenosine
_xchemistry
650 0 4 _aAdministration, Oral
650 0 4 _aAnimals
650 0 4 _aAnti-Bacterial Agents
_xchemical synthesis
650 0 4 _aBiological Availability
650 0 4 _aChromatography, Liquid
_xmethods
650 0 4 _aDNA Ligases
_xantagonists & inhibitors
650 0 4 _aDogs
650 0 4 _aDrug Design
650 0 4 _aDrug Evaluation, Preclinical
_xmethods
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aFluorine
_xchemistry
650 0 4 _aInhibitory Concentration 50
650 0 4 _aMass Spectrometry
_xmethods
650 0 4 _aModels, Chemical
650 0 4 _aNAD
_xchemistry
650 0 4 _aRats
700 1 _aGowravaram, Madhusudhan
700 1 _aHuynh, Hoan
700 1 _aLu, Min
700 1 _aMullen, George B
700 1 _aChen, Brendan
700 1 _aAlbert, Robert
700 1 _aO'Shea, Thomas J
700 1 _aRooney, Michael T
700 1 _aHu, Haiqing
700 1 _aNewman, Joseph V
700 1 _aMills, Scott D
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 22
_gno. 1
_gp. 85-9
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2011.11.071
_zAvailable from publisher's website
999 _c21377585
_d21377585