000			01615 a2200445 4500
005			20250511014443.0
264		0	_c19790523
008			197905s 0 0 eng d
022			_a0022-2623
024	7		_a10.1021/jm00188a008 _2doi
040			_aNLM _beng _cNLM
100	1		_aPortoghese, P S
245	0	0	_aSynthesis and pharmacologic characterization of an alkylating analogue (chlornaltrexamine) of naltrexone with ultralong-lasting narcotic antagonist properties. _h[electronic resource]
260			_bJournal of medicinal chemistry _cFeb 1979
300			_a168-73 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
650	0	4	_aAlkylating Agents _xchemical synthesis
650	0	4	_aAnalgesics
650	0	4	_aAnimals
650	0	4	_aHumans
650	0	4	_aIn Vitro Techniques
650	0	4	_aMale
650	0	4	_aMice
650	0	4	_aMolecular Conformation
650	0	4	_aMorphine _xantagonists & inhibitors
650	0	4	_aMorphine Dependence _xprevention & control
650	0	4	_aNaloxone _xanalogs & derivatives
650	0	4	_aNaltrexone _xanalogs & derivatives
650	0	4	_aNarcotic Antagonists _xchemical synthesis
650	0	4	_aNitrogen Mustard Compounds _xchemical synthesis
650	0	4	_aRats
650	0	4	_aReceptors, Opioid _xmetabolism
650	0	4	_aTime Factors
700	1		_aLarson, D L
700	1		_aJiang, J B
700	1		_aCaruso, T P
700	1		_aTakemori, A E
773	0		_tJournal of medicinal chemistry _gvol. 22 _gno. 2 _gp. 168-73
856	4	0	_uhttps://doi.org/10.1021/jm00188a008 _zAvailable from publisher's website
999			_c213513 _d213513