000 02019 a2200625 4500
005 20250516065020.0
264 0 _c20120503
008 201205s 0 0 eng d
022 _a1932-6203
024 7 _a10.1371/journal.pone.0027808
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aGong, Inna Y
245 0 0 _aClinical and genetic determinants of warfarin pharmacokinetics and pharmacodynamics during treatment initiation.
_h[electronic resource]
260 _bPloS one
_c2011
300 _ae27808 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aAlgorithms
650 0 4 _aAnticoagulants
_xpharmacokinetics
650 0 4 _aAryl Hydrocarbon Hydroxylases
_xgenetics
650 0 4 _aBlood Coagulation
_xdrug effects
650 0 4 _aCytochrome P-450 CYP2C9
650 0 4 _aCytochrome P-450 Enzyme System
_xgenetics
650 0 4 _aCytochrome P450 Family 4
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aFemale
650 0 4 _aGene Frequency
650 0 4 _aGenotype
650 0 4 _aHumans
650 0 4 _aKidney Function Tests
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aMixed Function Oxygenases
_xgenetics
650 0 4 _aProspective Studies
650 0 4 _aTissue Distribution
650 0 4 _aVitamin K
_xmetabolism
650 0 4 _aVitamin K Epoxide Reductases
650 0 4 _aWarfarin
_xpharmacokinetics
650 0 4 _aYoung Adult
700 1 _aSchwarz, Ute I
700 1 _aCrown, Natalie
700 1 _aDresser, George K
700 1 _aLazo-Langner, Alejandro
700 1 _aZou, GuangYong
700 1 _aRoden, Dan M
700 1 _aStein, C Michael
700 1 _aRodger, Marc
700 1 _aWells, Philip S
700 1 _aKim, Richard B
700 1 _aTirona, Rommel G
773 0 _tPloS one
_gvol. 6
_gno. 11
_gp. e27808
856 4 0 _uhttps://doi.org/10.1371/journal.pone.0027808
_zAvailable from publisher's website
999 _c21341153
_d21341153