000 01806 a2200529 4500
005 20250516064318.0
264 0 _c20120705
008 201207s 0 0 eng d
022 _a1476-5551
024 7 _a10.1038/leu.2011.322
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aFuka, G
245 0 0 _aSilencing of ETV6/RUNX1 abrogates PI3K/AKT/mTOR signaling and impairs reconstitution of leukemia in xenografts.
_h[electronic resource]
260 _bLeukemia
_cMay 2012
300 _a927-33 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aCell Line, Tumor
650 0 4 _aCore Binding Factor Alpha 2 Subunit
_xgenetics
650 0 4 _aGene Silencing
650 0 4 _aHumans
650 0 4 _aMice
650 0 4 _aPhosphatidylinositol 3-Kinases
_xmetabolism
650 0 4 _aPrecursor Cell Lymphoblastic Leukemia-Lymphoma
_xmetabolism
650 0 4 _aProto-Oncogene Proteins c-akt
_xmetabolism
650 0 4 _aProto-Oncogene Proteins c-ets
_xgenetics
650 0 4 _aRNA Interference
650 0 4 _aReal-Time Polymerase Chain Reaction
650 0 4 _aRepressor Proteins
_xgenetics
650 0 4 _aSignal Transduction
650 0 4 _aTOR Serine-Threonine Kinases
_xmetabolism
650 0 4 _aTransplantation, Heterologous
650 0 4 _aETS Translocation Variant 6 Protein
700 1 _aKantner, H-P
700 1 _aGrausenburger, R
700 1 _aInthal, A
700 1 _aBauer, E
700 1 _aKrapf, G
700 1 _aKaindl, U
700 1 _aKauer, M
700 1 _aDworzak, M N
700 1 _aStoiber, D
700 1 _aHaas, O A
700 1 _aPanzer-Grümayer, R
773 0 _tLeukemia
_gvol. 26
_gno. 5
_gp. 927-33
856 4 0 _uhttps://doi.org/10.1038/leu.2011.322
_zAvailable from publisher's website
999 _c21322119
_d21322119