| 000 | 01421 a2200385 4500 | ||
|---|---|---|---|
| 005 | 20250516062548.0 | ||
| 264 | 0 | _c20111220 | |
| 008 | 201112s 0 0 eng d | ||
| 022 | _a1536-3678 | ||
| 024 | 7 |
_a10.1097/MPH.0b013e31822aa4ec _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aLn, Ramya | |
| 245 | 0 | 0 |
_aIn silico engineering of L-asparaginase to have reduced glutaminase side activity for effective treatment of acute lymphoblastic leukemia. _h[electronic resource] |
| 260 |
_bJournal of pediatric hematology/oncology _cDec 2011 |
||
| 300 |
_a617-21 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 |
_aAsparaginase _xchemistry |
| 650 | 0 | 4 |
_aAsparagine _xchemistry |
| 650 | 0 | 4 | _aCatalytic Domain |
| 650 | 0 | 4 | _aChild |
| 650 | 0 | 4 | _aComputer Simulation |
| 650 | 0 | 4 | _aDrug Design |
| 650 | 0 | 4 |
_aGlutaminase _xchemistry |
| 650 | 0 | 4 |
_aGlutamine _xchemistry |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aLigands |
| 650 | 0 | 4 | _aMutagenesis, Site-Directed |
| 650 | 0 | 4 |
_aPrecursor Cell Lymphoblastic Leukemia-Lymphoma _xdrug therapy |
| 650 | 0 | 4 |
_aProtein Engineering _xmethods |
| 700 | 1 | _aDoble, Mukesh | |
| 700 | 1 | _aRekha, V P B | |
| 700 | 1 | _aPulicherla, K K | |
| 773 | 0 |
_tJournal of pediatric hematology/oncology _gvol. 33 _gno. 8 _gp. 617-21 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1097/MPH.0b013e31822aa4ec _zAvailable from publisher's website |
| 999 |
_c21272853 _d21272853 |
||