000 02278 a2200577 4500
005 20250516061206.0
264 0 _c20111208
008 201112s 0 0 eng d
022 _a1554-6578
024 7 _a10.1097/NEN.0b013e3182358e4e
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aGuemez-Gamboa, Alicia
245 0 0 _aActivation of NOX2 by the stimulation of ionotropic and metabotropic glutamate receptors contributes to glutamate neurotoxicity in vivo through the production of reactive oxygen species and calpain activation.
_h[electronic resource]
260 _bJournal of neuropathology and experimental neurology
_cNov 2011
300 _a1020-35 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aCalcium-Binding Proteins
_xmetabolism
650 0 4 _aCalpain
_xmetabolism
650 0 4 _aCorpus Striatum
_xdrug effects
650 0 4 _aDisease Models, Animal
650 0 4 _aDrug Interactions
650 0 4 _aExcitatory Amino Acid Agents
_xpharmacology
650 0 4 _aFluoresceins
650 0 4 _aGene Expression Regulation
_xdrug effects
650 0 4 _aGlutamic Acid
_xtoxicity
650 0 4 _aMembrane Glycoproteins
_xdeficiency
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMice, Knockout
650 0 4 _aMicrofilament Proteins
_xmetabolism
650 0 4 _aMicroglia
_xdrug effects
650 0 4 _aNADPH Oxidase 2
650 0 4 _aNADPH Oxidases
_xdeficiency
650 0 4 _aNeurons
_xdrug effects
650 0 4 _aNeurotoxicity Syndromes
_xetiology
650 0 4 _aOrganic Chemicals
650 0 4 _aPhosphopyruvate Hydratase
_xmetabolism
650 0 4 _aReactive Oxygen Species
_xmetabolism
650 0 4 _aReceptors, Immunologic
_xmetabolism
650 0 4 _aReceptors, Ionotropic Glutamate
_xmetabolism
650 0 4 _aReceptors, Metabotropic Glutamate
_xmetabolism
650 0 4 _aTime Factors
700 1 _aEstrada-Sánchez, Ana María
700 1 _aMontiel, Teresa
700 1 _aPáramo, Blanca
700 1 _aMassieu, Lourdes
700 1 _aMorán, Julio
773 0 _tJournal of neuropathology and experimental neurology
_gvol. 70
_gno. 11
_gp. 1020-35
856 4 0 _uhttps://doi.org/10.1097/NEN.0b013e3182358e4e
_zAvailable from publisher's website
999 _c21235099
_d21235099