000 01855 a2200457 4500
005 20250516060423.0
264 0 _c20120325
008 201203s 0 0 eng d
022 _a1557-3265
024 7 _a10.1158/1078-0432.CCR-11-0796
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aChang, Kwang-Yu
245 0 0 _aNovel phosphoinositide 3-kinase/mTOR dual inhibitor, NVP-BGT226, displays potent growth-inhibitory activity against human head and neck cancer cells in vitro and in vivo.
_h[electronic resource]
260 _bClinical cancer research : an official journal of the American Association for Cancer Research
_cNov 2011
300 _a7116-26 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aDrug Evaluation, Preclinical
650 0 4 _aHead and Neck Neoplasms
_xdrug therapy
650 0 4 _aHumans
650 0 4 _aImidazoles
_xtherapeutic use
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Nude
650 0 4 _aPhosphoinositide-3 Kinase Inhibitors
650 0 4 _aProtein Kinase Inhibitors
_xpharmacology
650 0 4 _aQuinolines
_xtherapeutic use
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aTOR Serine-Threonine Kinases
_xantagonists & inhibitors
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aTsai, Shan-Yin
700 1 _aWu, Ching-Ming
700 1 _aYen, Chia-Jui
700 1 _aChuang, Bin-Fay
700 1 _aChang, Jang-Yang
773 0 _tClinical cancer research : an official journal of the American Association for Cancer Research
_gvol. 17
_gno. 22
_gp. 7116-26
856 4 0 _uhttps://doi.org/10.1158/1078-0432.CCR-11-0796
_zAvailable from publisher's website
999 _c21211213
_d21211213