000 01944 a2200541 4500
005 20250516051854.0
264 0 _c20120110
008 201201s 0 0 eng d
022 _a1476-5500
024 7 _a10.1038/cgt.2011.45
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBhattacharyya, M
245 0 0 _aAn oncolytic adenovirus defective in pRb-binding (dl922-947) can efficiently eliminate pancreatic cancer cells and tumors in vivo in combination with 5-FU or gemcitabine.
_h[electronic resource]
260 _bCancer gene therapy
_cOct 2011
300 _a734-43 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdenocarcinoma
_xdrug therapy
650 0 4 _aAdenoviruses, Human
_xgenetics
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xtherapeutic use
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Survival
650 0 4 _aCombined Modality Therapy
650 0 4 _aCytopathogenic Effect, Viral
650 0 4 _aDeoxycytidine
_xanalogs & derivatives
650 0 4 _aFluorouracil
_xtherapeutic use
650 0 4 _aGene Deletion
650 0 4 _aGene Expression Regulation, Viral
_xdrug effects
650 0 4 _aHumans
650 0 4 _aKaplan-Meier Estimate
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMice, Nude
650 0 4 _aOncolytic Virotherapy
650 0 4 _aOncolytic Viruses
_xgenetics
650 0 4 _aPancreatic Neoplasms
_xdrug therapy
650 0 4 _aReceptors, Virus
_xmetabolism
650 0 4 _aRetinoblastoma Protein
_xmetabolism
650 0 4 _aVirus Replication
_xgenetics
650 0 4 _aXenograft Model Antitumor Assays
650 0 4 _aGemcitabine
700 1 _aFrancis, J
700 1 _aEddouadi, A
700 1 _aLemoine, N R
700 1 _aHalldén, G
773 0 _tCancer gene therapy
_gvol. 18
_gno. 10
_gp. 734-43
856 4 0 _uhttps://doi.org/10.1038/cgt.2011.45
_zAvailable from publisher's website
999 _c21080909
_d21080909