000 01615 a2200445 4500
005 20250516045614.0
264 0 _c20120208
008 201202s 0 0 eng d
022 _a1464-3391
024 7 _a10.1016/j.bmc.2011.06.073
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aAshoorzadeh, Amir
245 0 0 _aThe effect of sulfonate leaving groups on the hypoxia-selective toxicity of nitro analogs of the duocarmycins.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry
_cAug 2011
300 _a4851-60 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAlkanesulfonates
_xchemical synthesis
650 0 4 _aAntineoplastic Agents, Alkylating
_xchemical synthesis
650 0 4 _aCell Hypoxia
_xdrug effects
650 0 4 _aDNA
_xchemistry
650 0 4 _aDrug Design
650 0 4 _aDrug Screening Assays, Antitumor
650 0 4 _aDuocarmycins
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aIndoles
_xchemistry
650 0 4 _aNitro Compounds
_xchemical synthesis
650 0 4 _aProdrugs
_xchemical synthesis
650 0 4 _aPyrrolidinones
_xchemistry
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTumor Cells, Cultured
700 1 _aAtwell, Graham J
700 1 _aPruijn, Frederik B
700 1 _aWilson, William R
700 1 _aTercel, Moana
700 1 _aDenny, William A
700 1 _aStevenson, Ralph J
773 0 _tBioorganic & medicinal chemistry
_gvol. 19
_gno. 16
_gp. 4851-60
856 4 0 _uhttps://doi.org/10.1016/j.bmc.2011.06.073
_zAvailable from publisher's website
999 _c21015332
_d21015332