| 000 | 02299 a2200709 4500 | ||
|---|---|---|---|
| 005 | 20250516044904.0 | ||
| 264 | 0 | _c20120329 | |
| 008 | 201203s 0 0 eng d | ||
| 022 | _a1521-009X | ||
| 024 | 7 |
_a10.1124/dmd.111.040840 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aLiu, Lichuan | |
| 245 | 0 | 0 |
_aSignificant species difference in amide hydrolysis of GDC-0834, a novel potent and selective Bruton's tyrosine kinase inhibitor. _h[electronic resource] |
| 260 |
_bDrug metabolism and disposition: the biological fate of chemicals _cOct 2011 |
||
| 300 |
_a1840-9 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAgammaglobulinaemia Tyrosine Kinase |
| 650 | 0 | 4 |
_aAmides _xmetabolism |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aCells, Cultured |
| 650 | 0 | 4 | _aClinical Trials, Phase I as Topic |
| 650 | 0 | 4 | _aDogs |
| 650 | 0 | 4 | _aDouble-Blind Method |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 |
_aHepatocytes _xmetabolism |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aHydrolysis |
| 650 | 0 | 4 | _aMacaca fascicularis |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 |
_aMicrosomes, Liver _xmetabolism |
| 650 | 0 | 4 |
_aProtein Kinase Inhibitors _xmetabolism |
| 650 | 0 | 4 |
_aProtein-Tyrosine Kinases _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aPyrimidinones _xmetabolism |
| 650 | 0 | 4 | _aRandomized Controlled Trials as Topic |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 | _aRats, Sprague-Dawley |
| 650 | 0 | 4 | _aSpecies Specificity |
| 650 | 0 | 4 |
_aThiophenes _xmetabolism |
| 700 | 1 | _aHalladay, Jason S | |
| 700 | 1 | _aShin, Young | |
| 700 | 1 | _aWong, Susan | |
| 700 | 1 | _aCoraggio, Melis | |
| 700 | 1 | _aLa, Hank | |
| 700 | 1 | _aBaumgardner, Matthew | |
| 700 | 1 | _aLe, Hoa | |
| 700 | 1 | _aGopaul, Sashi | |
| 700 | 1 | _aBoggs, Jason | |
| 700 | 1 | _aKuebler, Peter | |
| 700 | 1 | _aDavis, John C | |
| 700 | 1 | _aLiao, X Charlene | |
| 700 | 1 | _aLubach, Joseph W | |
| 700 | 1 | _aDeese, Alan | |
| 700 | 1 | _aSowell, C Gregory | |
| 700 | 1 | _aCurrie, Kevin S | |
| 700 | 1 | _aYoung, Wendy B | |
| 700 | 1 | _aKhojasteh, S Cyrus | |
| 700 | 1 | _aHop, Cornelis E C A | |
| 700 | 1 | _aWong, Harvey | |
| 773 | 0 |
_tDrug metabolism and disposition: the biological fate of chemicals _gvol. 39 _gno. 10 _gp. 1840-9 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1124/dmd.111.040840 _zAvailable from publisher's website |
| 999 |
_c20994893 _d20994893 |
||