000 02215 a2200589 4500
005 20250516044800.0
264 0 _c20120504
008 201205s 0 0 eng d
022 _a1432-1041
024 7 _a10.1007/s00228-011-1094-4
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aAzuma, Junichi
245 0 0 _aThe relationship between clinical pharmacokinetics of aripiprazole and CYP2D6 genetic polymorphism: effects of CYP enzyme inhibition by coadministration of paroxetine or fluvoxamine.
_h[electronic resource]
260 _bEuropean journal of clinical pharmacology
_cJan 2012
300 _a29-37 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aAntipsychotic Agents
_xadverse effects
650 0 4 _aAripiprazole
650 0 4 _aBiotransformation
650 0 4 _aCytochrome P-450 CYP2D6
_xgenetics
650 0 4 _aCytochrome P-450 CYP2D6 Inhibitors
650 0 4 _aCytochrome P-450 CYP3A
650 0 4 _aCytochrome P-450 CYP3A Inhibitors
650 0 4 _aDrug Interactions
650 0 4 _aEnzyme Inhibitors
_xadverse effects
650 0 4 _aFluvoxamine
_xadverse effects
650 0 4 _aGenetic Association Studies
650 0 4 _aHalf-Life
650 0 4 _aHumans
650 0 4 _aJapan
650 0 4 _aMale
650 0 4 _aMetabolic Clearance Rate
_xdrug effects
650 0 4 _aParoxetine
_xadverse effects
650 0 4 _aPiperazines
_xadverse effects
650 0 4 _aPolymorphism, Genetic
650 0 4 _aQuinolones
_xadverse effects
650 0 4 _aSerotonin 5-HT2 Receptor Antagonists
_xadverse effects
650 0 4 _aSelective Serotonin Reuptake Inhibitors
_xadverse effects
650 0 4 _aYoung Adult
700 1 _aHasunuma, Tomoko
700 1 _aKubo, Masanori
700 1 _aMiyatake, Masaya
700 1 _aKoue, Toshiko
700 1 _aHigashi, Koushi
700 1 _aFujiwara, Tsutomu
700 1 _aKitahara, Sachiko
700 1 _aKatano, Tamiki
700 1 _aHara, Sumiko
773 0 _tEuropean journal of clinical pharmacology
_gvol. 68
_gno. 1
_gp. 29-37
856 4 0 _uhttps://doi.org/10.1007/s00228-011-1094-4
_zAvailable from publisher's website
999 _c20991441
_d20991441