000 01783 a2200505 4500
005 20250516044613.0
264 0 _c20111122
008 201111s 0 0 eng d
022 _a1464-3405
024 7 _a10.1016/j.bmcl.2011.06.045
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKerns, Jeffrey K
245 0 0 _aAzepanone-based inhibitors of human cathepsin S: optimization of selectivity via the P2 substituent.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cAug 2011
300 _a4409-15 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAlanine
_xchemistry
650 0 4 _aAzepines
_xchemical synthesis
650 0 4 _aBinding Sites
650 0 4 _aCathepsin K
_xantagonists & inhibitors
650 0 4 _aCathepsin L
_xantagonists & inhibitors
650 0 4 _aCathepsins
_xantagonists & inhibitors
650 0 4 _aComputer Simulation
650 0 4 _aHumans
650 0 4 _aNiacinamide
_xanalogs & derivatives
650 0 4 _aProtease Inhibitors
_xchemical synthesis
650 0 4 _aStereoisomerism
650 0 4 _aStructure-Activity Relationship
700 1 _aNie, Hong
700 1 _aBondinell, William
700 1 _aWiddowson, Katherine L
700 1 _aYamashita, Dennis S
700 1 _aRahman, Attiq
700 1 _aPodolin, Patricia L
700 1 _aCarpenter, Donald C
700 1 _aJin, Qi
700 1 _aRiflade, Benoit
700 1 _aDong, Xiaoyang
700 1 _aNevins, Neysa
700 1 _aKeller, Paul M
700 1 _aMitchell, Laura
700 1 _aTomaszek, Thaddeus
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 21
_gno. 15
_gp. 4409-15
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2011.06.045
_zAvailable from publisher's website
999 _c20986117
_d20986117