000			02242 a2200637 4500
005			20250516043201.0
264		0	_c20120227
008			201202s 0 0 eng d
022			_a1521-009X
024	7		_a10.1124/dmd.111.040675 _2doi
040			_aNLM _beng _cNLM
100	1		_aKalgutkar, Amit S
245	0	0	_aPreclinical species and human disposition of PF-04971729, a selective inhibitor of the sodium-dependent glucose cotransporter 2 and clinical candidate for the treatment of type 2 diabetes mellitus. _h[electronic resource]
260			_bDrug metabolism and disposition: the biological fate of chemicals _cSep 2011
300			_a1609-19 p. _bdigital
500			_aPublication Type: Journal Article; Randomized Controlled Trial
650	0	4	_aAdministration, Oral
650	0	4	_aAdult
650	0	4	_aAnimals
650	0	4	_aBiological Availability
650	0	4	_aBiotransformation
650	0	4	_aBridged Bicyclo Compounds, Heterocyclic _xpharmacokinetics
650	0	4	_aCaco-2 Cells
650	0	4	_aCross-Over Studies
650	0	4	_aCytochrome P-450 Enzyme Inhibitors
650	0	4	_aCytochrome P-450 Enzyme System _xmetabolism
650	0	4	_aDogs
650	0	4	_aDrug Evaluation, Preclinical
650	0	4	_aFemale
650	0	4	_aGlucuronosyltransferase _xmetabolism
650	0	4	_aHEK293 Cells
650	0	4	_aHepatocytes _xdrug effects
650	0	4	_aHumans
650	0	4	_aIntestinal Absorption
650	0	4	_aMale
650	0	4	_aMicrosomes, Liver _xenzymology
650	0	4	_aMiddle Aged
650	0	4	_aProtein Binding
650	0	4	_aRats
650	0	4	_aRats, Sprague-Dawley
650	0	4	_aSodium-Glucose Transport Proteins _xantagonists & inhibitors
650	0	4	_aYoung Adult
700	1		_aTugnait, Meera
700	1		_aZhu, Tong
700	1		_aKimoto, Emi
700	1		_aMiao, Zhuang
700	1		_aMascitti, Vincent
700	1		_aYang, Xin
700	1		_aTan, Beijing
700	1		_aWalsky, Robert L
700	1		_aChupka, Jonathan
700	1		_aFeng, Bo
700	1		_aRobinson, Ralph P
773	0		_tDrug metabolism and disposition: the biological fate of chemicals _gvol. 39 _gno. 9 _gp. 1609-19
856	4	0	_uhttps://doi.org/10.1124/dmd.111.040675 _zAvailable from publisher's website
999			_c20944565 _d20944565